ReviewSurgical infections2017
Management and Novel Adjuncts of Necrotizing Soft Tissue Infections.
Review in Surgical infections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Gender-Based Differences in Hirsch Index Among Academic Surgeons.The Journal of surgical research · 2019Pooled it
- Simple Wound Irrigation in the Postoperative Treatment for Surgically Drained Spontaneous Soft Tissue Abscesses: A Prospective, Randomized Controlled Trial.World journal of surgery · 2020Trial
- Phenotype-based appropriateness of IGM-enriched polyclonal immunoglobulin use in critical illness: report of an expert consensus.Journal of anesthesia, analgesia and critical care · 2026Review
- A Rare Case of Ascending Necrotizing Mediastinitis following Perforated Appendicitis: A Case Report.Surgical case reports · 2026Article
- Article
- Article
- Nutritional Support for Necrotizing Soft Tissue Infection Patients: From ICU to Outpatient Care.Journal of clinical medicine · 2025Review
- Management Outcome and Associated Factors of Necrotizing Soft Tissue Infections in an Ethiopian Tertiary Care Hospital: A-Five-Year Review.Ethiopian journal of health sciences · 2024Article
- Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.Trauma surgery & acute care open · 2024Article
- Outcome of necrotizing fasciitis and Fournier's gangrene with and without hyperbaric oxygen therapy: a retrospective analysis over 10 years.World journal of emergency surgery : WJES · 2022Article
- Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections.BMC medicine · 2022Article
- Fournier Gangrene in the Emergency Department: Diagnostic Dilemmas, Treatments and Current Perspectives.Open access emergency medicine : OAEM · 2020Review
- Traditional herbal treatment induced bilateral amputation of the feet in a five-year-old child: A case report.International journal of surgery case reports · 2020Article
- Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections.Nature communications · 2019Article
- Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient.Case reports in critical care · 2017Article
- Morbidity and Mortality of Necrotizing Fasciitis and Their Prognostic Factors in Children.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotizing soft tissue infections (NSTI) have been recognized for millennia and continue to impose considerable burden on both patient and society in terms of morbidity, death, and the allocation of resources. With improvements in the delivery of critical care, outcomes have improved, although disease-specific therapies are lacking. The basic principles of early diagnosis, of prompt and broad antimicrobial therapy, and of aggressive debridement have remained unchanged. Clearly novel and new therapeutics are needed to combat this persistently lethal disease. This review emphasizes the pillars of NSTI management and then summarizes the contemporary evidence supporting the incorporation of novel adjuncts to the pharmacologic and operative foundations of managing this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.