Evidence map›Paper›PMID 28375452›Full record

ReviewRheumatology (Oxford, England)2017

Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus.

Laurie S Davis, Andreas M Reimold

Registry-linked trialAbstract readReview
In one paragraph

Review in Rheumatology (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03426384 (Can Individualized Diet and Lifestyle Modifications Derived From Digital Therapeutics and Health Coaching Improve Symptoms of Systemic Lupus Erythematosus), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03426384 nacompletednot on this mapstarted 2018, after this paper: background citation

Can Individualized Diet and Lifestyle Modifications Derived From Digital Therapeutics and Health Coaching Improve Symptoms of Systemic Lupus Erythematosus

TypeinterventionalSponsorMymee Inc.Ran2018 to 2019Enrolled50ConditionsSystem, Lupus ErythematosusArmsMymee Program
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laurie S DavisRheumatic Diseases Division, Department of Internal Medicine, University of Texas Southwestern Medical Center.
Andreas M ReimoldRheumatic Diseases Division, Department of Internal Medicine, University of Texas Southwestern Medical Center.

Funding

Regulation and Consequences of Ets1 Downregulation in B CellsR01AI122720 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI GARRETT-SINHA, LEE ANN, SATTERTHWAITE, ANNE B · 2016 to 2020
$2.6M
Attenuation of Lupus by Foxo3R21AR067625 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI SATTERTHWAITE, ANNE B · 2015 to 2016
$391k
NIAID NIH HHS R01 AI122720NIAMS NIH HHS R21 AR067625
6 · The paper itself

Abstract

This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.

Indexed as

Antibodies, Monoclonal, HumanizedAntirheumatic AgentsAzathioprineCyclophosphamideDrug DiscoveryGlucocorticoidsHumansHydroxychloroquineImmunologic FactorsImmunosuppressive AgentsInterleukin-2Lupus Erythematosus, SystemicMethotrexateMolecular Targeted TherapyMycophenolic AcidRecombinant Fusion ProteinsAntibodies, Monoclonal, HumanizedAntirheumatic AgentsAzathioprinebelimumabCyclophosphamideepratuzumabGlucocorticoidsHydroxychloroquineImmunologic FactorsImmunosuppressive AgentsInterleukin-2MethotrexateMycophenolic AcidRecombinant Fusion ProteinsRituximabTACI receptor-IgG Fc fragment fusion proteintocilizumabUstekinumabVitamin DB cellsbiological therapiesclinical trials and methodsimmunotherapysystemic lupus erythematosus and autoimmunity

Identifiers

PMID28375452
PMCPMC5850311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.