Evidence map›Paper›PMID 28374977›Full record

ArticleJournal of cellular and molecular medicine2017

Hypoxic preconditioning-induced autophagy enhances survival of engrafted endothelial progenitor cells in ischaemic limb.

Pei Zhou, Yu-Zhen Tan, Hai-Jie Wang, Guo-Dong Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. c-kitStem cell reviews and reports · 2023
    Article
  7. Review
  8. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Vagal α7nAChR signaling regulates α7nAChRStem cell research & therapy · 2020
    Article
  15. Article
  16. Activation of Autophagy in Human Uterine Myometrium During Labor.Reproductive sciences (Thousand Oaks, Calif.) · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pei ZhouDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Yu-Zhen TanDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Hai-Jie WangDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.ORCID 0000-0002-1783-9617
Guo-Dong WangDepartment of Anatomy, Histology and Embryology, Shanghai Medical School of Fudan University, Shanghai, China.
Shanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent clinical studies have suggested that endothelial progenitor cells (EPCs) transplantation provides a modest benefit for treatment of the ischaemic diseases such as limb ischaemia. However, cell-based therapies have been limited by poor survival of the engrafted cells. This investigation was designed to establish optimal hypoxia preconditioning and evaluate effects of hypoxic preconditioning-induced autophagy on survival of the engrafted EPCs. Autophagy of CD34

Indexed as

AdenineAnimalsApoptosisAutophagyCell HypoxiaCells, CulturedCell SurvivalEndothelial Progenitor CellsHindlimbHypoxiaIschemiaIschemic PreconditioningRats, Sprague-DawleyStem Cell TransplantationVascular Endothelial Growth Factor Receptor-23-methyladenineAdenineVascular Endothelial Growth Factor Receptor-2autophagyendothelial progenitor cellsfibrinhypoxiasurvivaltransplantation

Identifiers

PMID28374977
PMCPMC5618704
OpenAlexW2604313126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.