Evidence map›Paper›PMID 28374832›Full record

Trial reportScientific reports2017

A randomized controlled trial of an ambulatory approach versus the hospital-based approach in managing suspected obstructive sleep apnea syndrome.

David S Hui, Susanna S Ng, Kin-Wang To, Fanny W Ko, Jenny Ngai, Ken K P Chan, Wing-Ho Yip, Tat-On Chan, Karen Yiu, Wilson W S Tam

Erratum issuedOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Observational
  7. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Upper airway collapsibility in patients with OSA treated with continuous positive airway pressure: a retrospective preliminary study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
  12. Predicting CPAP failure in patients with suspected sleep hypoventilation identified on ambulatory testing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Predictors of Obstructive Sleep Apnea on a Home Sleep Apnea Test After a Negative Attended Polysomnography.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

David S HuiDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Susanna S NgDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Kin-Wang ToDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Fanny W KoDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Jenny NgaiDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Ken K P ChanDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Wing-Ho YipDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Tat-On ChanDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Karen YiuDept of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Wilson W S TamAlice Lee Centre for Nursing Studies, National University of Singapore, Singapore.
Chinese University of Hong Kong · HKNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comparisons of home-based versus hospital-based approach in managing patients with suspected obstructive sleep apnoea syndrome(OSAS). A prospective, controlled CPAP parallel study of new referrals with suspected OSAS randomized into group A) home-based or B) hospital-based approach. Following detection of AHI ≥ 15/hr by Embletta sleep study (group A) or polysomnography (group B), patients received CPAP for 3 months after an overnight autoCPAP titration at home or in hospital respectively. Modified intention-to-treat analysis of those with AHI ≥ 15/hr on CPAP (n = 86 vs 86) showed no difference in Epworth sleepiness score, the primary endpoint, but greater improvement in Sleep-Apnoea-Quality-of-Life-Index[difference 0.3,(95%CI 0.02, 0.6), p = 0.033] at 3 months in group A. The mean costs for the patients in group A and group B were HK$8479(989) and HK$22,248(2407) respectively. The mean difference between groups was HK$-13,769(USD 1770 equivalent) per patient with 95% CI. (-14324, -13213), p < 0.001. The waiting time of patients with AHI ≥ 15/hr who were started on CPAP treatment from the first clinic consultation to the diagnostic sleep test, autoCPAP titration, and CPAP treatment was 189.6, 148.8 and 145.0 days shorter in group A than group B respectively. Home-based approach is non-inferior to hospital-based approach in managing patients with suspected OSAS, with shorter waiting time, and substantial cost savings.

Indexed as

Economics, HospitalAdultAgedAged, 80 and overAmbulatory CareContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedPolysomnographySleep Apnea, Obstructive

Identifiers

PMID28374832
PMCPMC5379203
OpenAlexW2604288779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.