Evidence map›Paper›PMID 28374757›Full record

ArticleScientific reports2017

Urine metabolomics in neonates with late-onset sepsis in a case-control study.

Kosmas Sarafidis, Anastasia Chrysovalantou Chatziioannou, Agathi Thomaidou, Helen Gika, Emmanouel Mikros, Dimitra Benaki, Elisavet Diamanti, Charalampos Agakidis, Nikolaos Raikos, Vasiliki Drossou and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. C-reactive protein for diagnosing late-onset infection in newborn infants.The Cochrane database of systematic reviews · 2019
    Pooled it
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  7. Metabolomics in neonatal sepsis: A critical appraisal of current evidence.Computational and structural biotechnology journal · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kosmas Sarafidis1st Department of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Anastasia Chrysovalantou ChatziioannouSchool of Chemistry, Aristotle University of Thessaloniki, Greece.
Agathi Thomaidou1st Department of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Helen GikaLaboratory of Forensic Medicine and Toxicology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Emmanouel MikrosSchool of Pharmacy, National and Kapodistrian University of Athens, Greece.
Dimitra BenakiSchool of Pharmacy, National and Kapodistrian University of Athens, Greece.
Elisavet Diamanti1st Department of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Charalampos Agakidis1st Department of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Nikolaos RaikosLaboratory of Forensic Medicine and Toxicology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Vasiliki Drossou1st Department of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece.
Georgios TheodoridisSchool of Chemistry, Aristotle University of Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although late-onset sepsis (LOS) is a major cause of neonatal morbidity and mortality, biomarkers evaluated in LOS lack high diagnostic accuracy. In this prospective, case-control, pilot study, we aimed to determine the metabolic profile of neonates with LOS. Urine samples were collected at the day of initial LOS evaluation, the 3

Indexed as

MetabolomicsUrinalysisBiomarkersCase-Control StudiesChromatography, LiquidHumansInfant, NewbornLate Onset DisordersMagnetic Resonance SpectroscopyNeonatal SepsisPilot ProjectsProspective StudiesTandem Mass SpectrometryUrineBiomarkers

Identifiers

PMID28374757
PMCPMC5379623
OpenAlexW2604321141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.