Evidence map›Paper›PMID 28374663›Full record

Trial reportPsychological medicine2017

Efficacy of meaning-centered group psychotherapy for cancer survivors: a randomized controlled trial.

N van der Spek, J Vos, C F van Uden-Kraan, W Breitbart, P Cuijpers, K Holtmaat, B I Witte, R A E M Tollenaar, I M Verdonck-de Leeuw

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 8 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03996642 nacompletednot on this mapstarted 2019, after this paper: background citation

Feasibility of Delivering an Avatar Life-review Intervention to Support Patients With Active Cancer

TypeinterventionalSponsorVirginia Commonwealth UniversityRan2019 to 2019Enrolled11ConditionsCancerArmsAvatar Life Review
NCT05197348 nacompletednot on this mapstarted 2021, after this paper: background citation

Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: a Protocol Study of a Randomized Control Trial

TypeinterventionalSponsorUniversity of ValenciaRan2021 to 2023Enrolled92ConditionsCancerArmsMeaning-Centered Group Psychotherapy (MCP)., Cognitive Behavioral Psychotherapy (CBT).
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 8 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
  2. A systematic review on the effects of logotherapy and meaning-centered therapy on psychological and existential symptoms in women with breast and gynecological cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Effects of meaning-based psychotherapy on post-traumatic growth and death anxiety in patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
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  5. Resilience Interventions Conducted in Western and Eastern Countries-A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  11. Effects of family-centered positive psychological intervention on psychological health and quality of life in patients with breast cancer and their caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  20. The EORTC QLU-C10D is a valid cancer-specific preference-based measure for cost-utility and health technology assessment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

N van der SpekDepartment of Clinical Psychology,VU University,Amsterdam,the Netherlands.
J VosDepartment of Psychology,University of Roehampton,London,UK.
C F van Uden-KraanDepartment of Clinical Psychology,VU University,Amsterdam,the Netherlands.
W BreitbartDepartment of Psychiatry and Behavioral Sciences,Memorial Sloan-Kettering Cancer Center,New York, NY,USA.
P CuijpersDepartment of Clinical Psychology,VU University,Amsterdam,the Netherlands.
K HoltmaatDepartment of Clinical Psychology,VU University,Amsterdam,the Netherlands.
B I WitteEpidemiology & Biostatistics,VU University Medical Center,Amsterdam,the Netherlands.
R A E M TollenaarDepartment of Surgery,Leiden University Medical Center,Leiden,The Netherlands.
I M Verdonck-de LeeuwDepartment of Clinical Psychology,VU University,Amsterdam,the Netherlands.
Leiden University Medical Center · NLMemorial Sloan Kettering Cancer Center · USUniversity of Roehampton · GB

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
Computational prediction of gut microbiome-mediated drug metabolismR41TR003571 · NCATS · NEXILICO, INC. · PI MOFRAD, MOHAMMAD RK, SHIRAZI, FATEMEH · 2021 to 2022
$380k
NCATS NIH HHS R41 TR003571NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the efficacy of meaning-centered group psychotherapy for cancer survivors (MCGP-CS) to improve personal meaning, compared with supportive group psychotherapy (SGP) and care as usual (CAU).

methodA total of 170 cancer survivors were randomly assigned to one of the three study arms: MCGP-CS (n = 57); SGP (n = 56); CAU (n = 57). The primary outcome measure was the Personal Meaning Profile (PMP; total score). Secondary outcome measures were subscales of the PMP, psychological well-being (Scales of Psychological Well-being; SPWB), post-traumatic growth (Posttraumatic Growth Inventory), Mental Adjustment to Cancer (MAC), optimism (Life Orientation Test-Revised), hopelessness (Beck's Hopelessness Scale), psychological distress (anxiety and depression, Hospital Anxiety and Depression Scale; HADS) and quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire; EORTC QLQ-C30). Outcome measures were assessed before randomization, post-intervention, and after 3 and 6 months of follow-up (FU).

resultsLinear mixed model analyses (intention-to-treat) showed significant differences between MCGP-CS, SGP and CAU on the total PMP score, and on (sub)scales of the PMP, SPWB, MAC and HADS. Post-hoc analyses showed significantly stronger treatment effects of MCGP-CS compared with CAU on personal meaning (d = 0.81), goal-orientedness (d = 1.07), positive relations (d = 0.59), purpose in life (d = 0.69); fighting spirit (d = 0.61) (post-intervention) and helpless/hopeless (d = -0.87) (3 months FU); and distress (d = -0.6) and depression (d = -0.38) (6 months FU). Significantly stronger effects of MCGP-CS compared with SGP were found on personal growth (d = 0.57) (3 months FU) and environmental mastery (d = 0.66) (6 months FU).

conclusionsMCGP-CS is an effective intervention for cancer survivors to improve personal meaning, psychological well-being and mental adjustment to cancer in the short term, and to reduce psychological distress in the long run.

Indexed as

Outcome Assessment, Health CarePersonal SatisfactionAdultAgedAnxietyCancer SurvivorsDepressionFemaleHopeHumansMaleMiddle AgedOptimismPsychotherapy, GroupQuality of Lifecancer survivorsGroup psychotherapymeaningpsychological well-beingRCT

Identifiers

PMID28374663
PMCPMC5501751
OpenAlexW2604525151

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.