Evidence map›Paper›PMID 28374661›Full record

Trial reportPsychological medicine2017

An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia.

W T Chien, D Bressington, A Yip, T Karatzias

Erratum issued 2 registry-linked trialsAbstract readMulticenter StudyPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01667601 nacompletednot on this map

The Effectiveness of a Mindfulness-based Illness Management Program for Chinese Patients With Schizophrenia: An Randomised Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2010 to 2017Enrolled449ConditionsSchizophreniaArmsRoutine Care, Mindfulness-based program, Psychoeducation group
NCT03632278 naunknown statusnot on this mapstarted 2018, after this paper: background citation

The Effectiveness of a Mindfulness Psychoeducation Program on Emotional Regulation for People With Schizophrenia: A Pilot Randomized Control Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2018 to 2019Enrolled58ConditionsSchizophreniform DisordersArmsMindfulness psychoeducation Programme
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  5. Mindfulness-Based Interventions for People with Schizophrenia: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
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  6. Self-management interventions for people with severe mental illness: systematic review and meta-analysis.The British journal of psychiatry : the journal of mental science · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

W T ChienMental Health Care Research Group,School of Nursing,Faculty of Health and Social Sciences,The Hong Kong Polytechnic University,Hung Hom,Hong Kong,People's Republic of China.
D BressingtonMental Health Care Research Group,School of Nursing,Faculty of Health and Social Sciences,The Hong Kong Polytechnic University,Hung Hom,Hong Kong,People's Republic of China.
A YipMental Health Care Research Group,School of Nursing,Faculty of Health and Social Sciences,The Hong Kong Polytechnic University,Hung Hom,Hong Kong,People's Republic of China.
T KaratziasSchool of Health & Social Care,Edinburgh Napier University,Edinburgh,UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to test a mindfulness-based psychoeducation group (MBPEG), v. a conventional psychoeducation group (CPEG) v. treatment as usual (TAU), in patients with schizophrenia-spectrum disorders over a 24-month follow-up.

methodThis single-blind, multi-site, pragmatic randomized controlled trial was conducted in six community treatment facilities across three countries (Hong Kong, mainland China and Taiwan). Patients were randomly allocated to one of the treatment conditions, and underwent 6 months of treatment. The primary outcomes were changes in duration of re-hospitalizations and mental state (Positive and Negative Syndrome Scale; PANSS) between baseline and 1 week, and 6, 12 and 18 months post-treatment.

resultsA total of 300 patients in each country were assessed for eligibility between October 2013 and 30 April 2014, 38 patients per country (n = 342) were assigned to each treatment group and included in the intention-to-treat analysis. There was a significant difference in the length of re-hospitalizations between the three groups over 24 months (F 2,330 = 5.23, p = 0.005), with MBPEG participants having a shorter mean duration of re-hospitalizations than those in the other groups. The MBPEG and CPEG participants had significant differential changes in proportional odds ratios of complete remission (all individual PANSS items <3) over the 24-month follow-up (37 and 26%, respectively), as opposed to only 7.2% of the TAU group (χ2 = 8.9 and 8.0, p = 0.001 and 0.003, relative risk = 3.5 and 3.1, 95% confidence interval 2.0-7.2 and 1.6-6.3).

conclusionsCompared with TAU and CPEG, MBPEG improves remission and hospitalization rates of people with schizophrenia spectrum disorders over 24 months.

Indexed as

MindfulnessOutcome Assessment, Health CarePatient Education as TopicPatient ReadmissionSchizophreniaAdolescentAdultChinaFemaleFollow-Up StudiesHong KongHumansMaleMiddle AgedSingle-Blind MethodTaiwanMindfulness-based interventionspsychoeducationrandomized controlled trialsre-hospitalizationschizophrenia spectrum disorders

Identifiers

PMID28374661
PMCPMC5551382

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.