Evidence map›Paper›PMID 28374099›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Dalbergioidin (DAL) protects MC3T3-E1 osteoblastic cells against H

Yu-Qin Jin, Jia-Ling Li, Jin-Dong Chen, Chang-Liang Xu, Huang Li

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yu-Qin JinDepartment of Orthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, 210008, China.
Jia-Ling LiDepartment of Orthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, 210008, China.
Jin-Dong ChenDepartment of Orthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, 210008, China.
Chang-Liang XuKey Laboratory of SATCM for Empirical Formulae Evaluation and Achievements Transformation, The No. 1 Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China.
Huang LiDepartment of Orthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, 210008, China. lihuang76@nju.edu.cn.
Nanjing University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) is a pivotal pathogenic factor in the development of osteoporosis. Dalbergioidin (DAL) can be isolated from Uraria crinite, an edible herb used as a natural food for childhood skeletal dysplasia. Recent research has implicated DAL as having an antiosteoporosis effect, although the mechanism of this is unclear. We used an effective oxidative stress model, induced by hydrogen peroxide (H

Indexed as

Alkaline PhosphataseAnimalsApoptosisCells, CulturedChromonesHydrogen PeroxideMiceOsteoblastsOsteoporosisPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionSmad1 ProteinAlkaline PhosphataseChromonesdalbergioidinHydrogen PeroxidePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSmad1 ProteinSmad1 protein, mouseApoptosisDalbergioidin (DAL)OsteoporosisOxidative stressPI3K/AKT/SMAD1 pathway

Identifiers

PMID28374099
OpenAlexW2604912047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.