Evidence map›Paper›PMID 28373915›Full record

ReviewNeural plasticity2017

Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art.

Marialuisa Gandolfi, Nicola Smania, Antonio Vella, Alessandro Picelli, Salvatore Chirumbolo

Open access · goldAbstract readReview
In one paragraph

Review in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. State of the science in inflammation and stroke recovery: A systematic review.Annals of physical and rehabilitation medicine · 2022
    Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Proenkephalin A as Potential Prognostic Biomarker in Acute Ischemic Stroke.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marialuisa GandolfiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; UOC Neurorehabilitation, AOUI Verona, Verona, Italy.ORCID 0000-0002-0877-4807
Nicola SmaniaDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; UOC Neurorehabilitation, AOUI Verona, Verona, Italy.ORCID 0000-0001-7630-1887
Antonio VellaImmunology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Alessandro PicelliDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; UOC Neurorehabilitation, AOUI Verona, Verona, Italy.ORCID 0000-0002-3558-8276
Salvatore ChirumboloDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0003-1789-8307
University of Verona · ITAzienda Ospedaliera Universitaria Integrata Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the increasing update of the biomolecular scientific literature, biomarkers in stroke have reached an outstanding and remarkable revision in the very recent years. Besides the diagnostic and prognostic role of some inflammatory markers, many further molecules and biological factors have been added to the list, including tissue derived cytokines, growth factor-like molecules, hormones, and microRNAs. The literatures on brain derived growth factor and other neuroimmune mediators, bone-skeletal muscle biomarkers, cellular and immunity biomarkers, and the role of microRNAs in stroke recovery were reviewed. To date, biomarkers represent a possible challenge in the diagnostic and prognostic evaluation of stroke onset, pathogenesis, and recovery. Many molecules are still under investigation and may become promising and encouraging biomarkers. Experimental and clinical research should increase this list and promote new discoveries in this field, to improve stroke diagnosis and treatment.

Indexed as

BiomarkersBrain-Derived Neurotrophic FactorCytokinesHumansIntercellular Signaling Peptides and ProteinsRecovery of FunctionStrokeStroke RehabilitationBiomarkersbrain-derived growth factorBrain-Derived Neurotrophic FactorCytokinesIntercellular Signaling Peptides and Proteins

Identifiers

PMID28373915
PMCPMC5360976
OpenAlexW2594405551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.