ArticleScientific reports2017
Fast preparation of RG-I enriched ultra-low molecular weight pectin by an ultrasound accelerated Fenton process.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 121 citations in OpenAlex.
- Decoding dietary pectin: from structural complexity and microbial CAZyme-PUL networks to cross-feeding and host-beneficial metabolites.Gut microbes · 2026Review
- Green Preparation, Structural Characterization, and Antioxidant Activity of Apple Pectin Oligosaccharides Obtained by Hydrogen Peroxide Degradation.Molecules (Basel, Switzerland) · 2026Article
- Circular valorization of green leafy side streams via pressurized liquid extraction techniques for recovery of bioactive compounds.Food chemistry: X · 2025Article
- Structural Characteristics, Gelling Properties,Foods (Basel, Switzerland) · 2025Article
- Pectic polysaccharides from Tartary buckwheat sprouts: Effects of ultrasound-assisted Fenton treatment and mild alkali treatment on their physicochemical characteristics and biological functions.Ultrasonics sonochemistry · 2024Article
- The Preparation and Potential Bioactivities of Modified Pectins: A Review.Foods (Basel, Switzerland) · 2023Review
- Expression of ExogenousBiology · 2022Article
- Chain conformations and steady-shear viscosity properties of pectic polysaccharides from apple and tomato.Food chemistry: X · 2022Article
- Article
- Characterization, biological evaluation and molecular docking of mulberry fruit pectin.Scientific reports · 2020Article
- Article
- Ultrasonic-Assisted Extraction, Structural Characterization, Chain Conformation, and Biological Activities of a Pectic-Polysaccharide from Okra (Molecules (Basel, Switzerland) · 2020Article
- Hybrid Advanced Oxidation Processes Involving Ultrasound: An Overview.Molecules (Basel, Switzerland) · 2019Review
- Bottom-up and top-down profiling of pentosan polysulfate.The Analyst · 2019Article
- Preparation of low molecular weight heparin using an ultrasound-assisted Fenton-system.Ultrasonics sonochemistry · 2019Article
- Oxidative DNA damage induced by ROS-modulating agents with the ability to target DNA: A comparison of the biological characteristics of citrus pectin and apple pectin.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pectin, a natural polysaccharide found in the cell wall of most higher plant such as citrus, has drawn much attention due to its potential beneficial role in facilitating the treatment of many diseases like cancer, hyper cholesterol and diabetes. However, the broad application of pectin faces great limitations as the large molecular size of pectin severely prevents its bioavailability in vivo. In this study, we report an effective and highly convenient approach to degrade natural pectin into lower molecular pectin. By combining ultrasound with Fenton system (US-Fenton), we show that ultrasound synergistically enhances the efficiency of Fenton reaction to degrade pectin into 5.5 kDa within only 35 minutes. Importantly, RG-I domain, the most effective portion of natural pectin, was well preserved and highly enriched. In addition, the antioxidant activities of US-Fenton-treated pectin was significantly elevated. The mechanism of this novel observation was further investigated through the multiple structural analyses including HPLC, IR and NMR. Taken together, we present a novel and convenient approach to generate ultra-low molecular weight pectin with high efficiency and higher bioactivity. We expect our approach will have broader applications in improving the bioavailability and bioactivity of other polysaccharide-based natural compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.