Evidence map›Paper›PMID 28373577›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Parathyroid hormone controls paracellular Ca

Tadatoshi Sato, Marie Courbebaisse, Noriko Ide, Yi Fan, Jun-Ichi Hanai, Jovana Kaludjerovic, Michael J Densmore, Quan Yuan, Hakan R Toka, Martin R Pollak and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 69 citations in OpenAlex.

  1. Endocrine regulation of uromodulin in aging.Frontiers in endocrinology · 2026
    Review
  2. Review
  3. Article
  4. Control of renal calcium permeability via a tight junctional claudin switch.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Claudins in Cancer: A Current and Future Therapeutic Target.International journal of molecular sciences · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. The role of claudins in homeostasis.Nature reviews. Nephrology · 2023
    Review
  14. Nephrocalcinosis in a 3-year-old child with hypocalcemia: Answers.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  15. Review
  16. Physiology of a Forgotten Electrolyte-Magnesium Disorders.Advances in kidney disease and health · 2023
    Review
  17. Review
  18. Review
  19. Lysine-specific demethylase 1 as a corepressor of mineralocorticoid receptor.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  20. Molecular mechanisms altering tubular calcium reabsorption.Pediatric nephrology (Berlin, Germany) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Tadatoshi SatoDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Marie CourbebaisseDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Noriko IdeDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Yi FanDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Jun-Ichi HanaiDivision of Interdisciplinary Medicine and Biotechnology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115.
Jovana KaludjerovicDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Michael J DensmoreDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Quan YuanDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115.
Hakan R TokaDivision of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115.
Martin R PollakDivision of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115.
Jianghui HouDepartment of Internal Medicine, Washington University Renal Division, Washington University, St. Louis, MO 63130.
Beate LanskeDivision of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115; beate_lanske@hsdm.harvard.edu.
Harvard University · USBeth Israel Deaconess Medical Center · USMassachusetts General Hospital · USDélégation Paris 5 · FRWashington University in St. Louis · US

Funding

BIOCHEMICAL AND BIOPHYSICAL NATURE OF CLAUDIN-16 AND CLAUDIN-19 CHANNELSR01DK084059 · NIDDK · WASHINGTON UNIVERSITY · PI HOU, JIANGHUI · 2010 to 2018
$2.9M
The Regulation of the Parathyroid GlandR01DK097105 · NIDDK · HARVARD MEDICAL SCHOOL · PI MANNSTADT, BEATE · 2012 to 2015
$2.2M
NIDDK NIH HHS R01 DK084059NIDDK NIH HHS R01 DK097105
6 · The paper itself

Abstract

Renal Ca

Indexed as

Gene Expression RegulationAnimalsCalciumClaudinsExtremitiesMiceMice, Inbred C57BLMice, KnockoutParathyroid HormonePromoter Regions, GeneticReceptor, Parathyroid Hormone, Type 1Signal TransductionTight JunctionsCalciumclaudin 14ClaudinsParathyroid HormoneReceptor, Parathyroid Hormone, Type 1CLDN14hypercalciuriamouse kidneyparacellularPTH1R

Identifiers

PMID28373577
PMCPMC5402431
OpenAlexW2605144963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.