Evidence map›Paper›PMID 28373552›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Phosphatidylinositol 3-phosphate-binding protein AtPH1 controls the localization of the metal transporter NRAMP1 in

Astrid Agorio, Jérôme Giraudat, Michele Wolfe Bianchi, Jessica Marion, Christelle Espagne, Loren Castaings, Françoise Lelièvre, Catherine Curie, Sébastien Thomine, Sylvain Merlot

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
12.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Cargo Sorting Zones in Plant Trans-Golgi Network.Sub-cellular biochemistry · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Phafins Are More Than Phosphoinositide-Binding Proteins.International journal of molecular sciences · 2023
    Review
  8. Review
  9. CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Effects of Fe and Mn Deficiencies on the Root Protein Profiles of Tomato (International journal of molecular sciences · 2022
    Article
  12. Review
  13. International journal of molecular sciences · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Astrid AgorioInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Jérôme GiraudatInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Michele Wolfe BianchiInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Jessica MarionInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Christelle EspagneInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Loren CastaingsLaboratoire de Biochimie et Physiologie Moléculaire des Plantes, CNRS, UMR 5004, Institut de Biologie Intégrative des Plantes, Montpellier, France.
Françoise LelièvreInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
Catherine CurieLaboratoire de Biochimie et Physiologie Moléculaire des Plantes, CNRS, UMR 5004, Institut de Biologie Intégrative des Plantes, Montpellier, France.
Sébastien ThomineInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France; sylvain.merlot@i2bc.paris-saclay.fr sebastien.thomine@i2bc.paris-saclay.fr.
Sylvain MerlotInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France; sylvain.merlot@i2bc.paris-saclay.fr sebastien.thomine@i2bc.paris-saclay.fr.ORCID 0000-0002-9352-1184
Université Paris-Sud · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"Too much of a good thing" perfectly describes the dilemma that living organisms face with metals. The tight control of metal homeostasis in cells depends on the trafficking of metal transporters between membranes of different compartments. However, the mechanisms regulating the location of transport proteins are still largely unknown. Developing

Indexed as

Amino Acid SequenceArabidopsisArabidopsis ProteinsBase SequenceCation Transport ProteinsIon TransportMetalsMutationNatural Resistance-associated Macrophage Protein 1PhenotypePhosphatidylinositol PhosphatesPlant RootsArabidopsis ProteinsCation Transport ProteinsMetalsNatural Resistance-associated Macrophage Protein 1phosphatidylinositol 3-phosphatePhosphatidylinositol Phosphateslate endosomemetal transportNRAMPphosphatidylinositol 3-phosphatevacuole

Identifiers

PMID28373552
PMCPMC5402440
OpenAlexW2604596974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.