Evidence map›Paper›PMID 28373486›Full record

ArticleJournal of lipid research2017

Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals.

Johanna von Gerichten, Kerstin Schlosser, Dominic Lamprecht, Ivan Morace, Matthias Eckhardt, Dagmar Wachten, Richard Jennemann, Hermann-Josef Gröne, Matthias Mack, Roger Sandhoff

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 46 citations in OpenAlex.

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  11. mBio · 2024
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  15. Characterization of a Glycolipid Synthase Producing α-Galactosylceramide inInternational journal of molecular sciences · 2022
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Johanna von GerichtenLipid Pathobiochemistry Group German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0002-9224-5296
Kerstin SchlosserDepartment of Biotechnology, Institute for Technical Microbiology, Mannheim University of Applied Sciences, Mannheim, Germany.
Dominic LamprechtLipid Pathobiochemistry Group German Cancer Research Center, Heidelberg, Germany.
Ivan MoraceDepartment of Molecular and Cellular Pathology, German Cancer Research Center, Heidelberg, Germany.
Matthias EckhardtInstitute of Biochemistry and Molecular Biology and Center for Rare Diseases University of Bonn, Bonn, Germany.
Dagmar WachtenMinerva Max Planck Research Group, Molecular Physiology, Center of Advanced European Studies and Research, Bonn, Germany.ORCID 0000-0003-4800-6332
Richard JennemannDepartment of Molecular and Cellular Pathology, German Cancer Research Center, Heidelberg, Germany.
Hermann-Josef GröneDepartment of Molecular and Cellular Pathology, German Cancer Research Center, Heidelberg, Germany.ORCID 0000-0003-3613-2649
Matthias MackDepartment of Biotechnology, Institute for Technical Microbiology, Mannheim University of Applied Sciences, Mannheim, Germany.ORCID 0000-0002-7753-2422
Roger SandhoffLipid Pathobiochemistry Group German Cancer Research Center, Heidelberg, Germany r.sandhoff@dkfz.de.
Heidelberg University · DEMannheim University of Applied Sciences · DEGerman Cancer Research Center · DECenter of Advanced European Studies and Research · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in several diseases, such as sphingolipidosis, diabetes, chronic kidney diseases, or cancer. In contrast,

Indexed as

AnimalsBacteriaCeramidesGastrointestinal MicrobiomeHumansMiceStereoisomerismCeramidesBacteroides fragiliscerebrosideelectrospray ionization-tandem mass spectrometryfatty acid 2-hydroylasegalactosylceramidegalactosylsphingosineglobotriaosylceramide synthaseglucocerebrosideglucopsychosineglucosidase beta 2glucosylceramideglucosylceramide synthaseglucosylsphingosinehydrophilic interaction chromatographykidneyKRN7000livermicrobiotapsychosineα-galactosylceramide

Identifiers

PMID28373486
PMCPMC5454501
OpenAlexW2604752014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.