Evidence map›Paper›PMID 28373409›Full record

ArticlePhysiological reports2017

Activation of TGF-

Zhiwei Liu, Fansheng Kong, Jefferson E Vallance, Eleana Harmel-Laws, Surya Amarachintha, Kris A Steinbrecher, Michael J Rosen, Sandip Bhattacharyya

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. AphaMaxNutrients · 2020
    Article
  9. Review
  10. Review
  11. Activation of TGF-Physiological reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhiwei LiuDepartment of Pediatrics, Center for Prevention of Preterm Birth Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati Ohio.
Fansheng KongDepartment of Pediatrics, Center for Prevention of Preterm Birth Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati Ohio.
Jefferson E VallanceDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine, Cincinnati, Ohio.
Eleana Harmel-LawsDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine, Cincinnati, Ohio.
Surya AmarachinthaDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine, Cincinnati, Ohio.
Kris A SteinbrecherDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine, Cincinnati, Ohio.
Michael J RosenDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine, Cincinnati, Ohio.
Sandip BhattacharyyaDepartment of Pediatrics, Center for Prevention of Preterm Birth Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati Ohio Sandip.Bhattacharyya@cchmc.org.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Theresa Alenghat · 2007 to 2026
$24.4M
Th2 Cytokines and Signaling in Pediatric Inflammatory Bowel DiseaseK23DK094832 · NIDDK · VANDERBILT UNIVERSITY · PI ROSEN, MICHAEL J · 2013 to 2017
$900k
NIDDK NIH HHS K23 DK094832NIDDK NIH HHS P30 DK078392
6 · The paper itself

Abstract

The etiology and mechanisms for inflammatory bowel disease (IBD) are incompletely known. Determination of new, clinically important mechanisms for intestinal inflammation is imperative for developing effective therapies to treat IBD We sought to define a widespread mechanism for colon mucosal inflammation via the activation of TGF-

Indexed as

Adaptor Proteins, Signal TransducingAdolescentAnimalsChildChild, PreschoolColonFemaleHumansInflammatory Bowel DiseasesInterleukin-10Intestinal MucosaMaleMiceMice, KnockoutAdaptor Proteins, Signal TransducingIL10 protein, mouseInterleukin-10TAB3 protein, humanGlucocorticoidintestinal inflammationTAK1

Identifiers

PMID28373409
PMCPMC5392505
OpenAlexW2604784170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.