Evidence map›Paper›PMID 28373277›Full record

ArticleThe Journal of biological chemistry2017

Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea.

Margaret R Heider, Brett W Burkhart, Thomas J Santangelo, Andrew F Gardner

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Ribonucleotide errors, RNase HII, and ribonucleotide excision repair.Critical reviews in biochemistry and molecular biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Ribonucleotide incorporation into DNA during DNA replication and its consequences.Critical reviews in biochemistry and molecular biology · 2021
    Review
  13. Article
  14. Open biology · 2020
    Review
  15. Review
  16. Impact of 1,The Journal of biological chemistry · 2020
    Article
  17. Article
  18. Article
  19. Unlike theThe Journal of biological chemistry · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Margaret R HeiderFrom New England Biolabs, Inc., Ipswich, Massachusetts 01938 and.
Brett W Burkhartthe Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80521.
Thomas J Santangelothe Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80521.
Andrew F GardnerFrom New England Biolabs, Inc., Ipswich, Massachusetts 01938 and gardner@neb.com.
Colorado State University · USNew England Biolabs (United States) · US

Funding

Mechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5M
NIGMS NIH HHS R01 GM100329
6 · The paper itself

Abstract

Incorporation of ribonucleotides during DNA replication has severe consequences for genome stability. Although eukaryotes possess a number of redundancies for initiating and completing repair of misincorporated ribonucleotides, archaea such as

Indexed as

DNA Breaks, Single-StrandedArchaeal ProteinsDNA, ArchaealDNA LigasesDNA Polymerase betaDNA RepairRibonuclease HThermococcusArchaeal ProteinsDNA, ArchaealDNA LigasesDNA Polymerase betaRibonuclease HarchaeaDNA damageDNA repairDNA replicationDNA synthesisenzyme kineticspre-steady-state kineticsribonucleotide excision repairRNaseH2

Identifiers

PMID28373277
PMCPMC5448109
OpenAlexW2604522302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.