Evidence map›Paper›PMID 28373255›Full record

ArticleBMJ open2017

Associations of moderate-to-vigorous-intensity physical activity and body mass index with glycated haemoglobin within the general population: a cross-sectional analysis of the 2008 Health Survey for England.

Kishan Bakrania, Thomas Yates, Charlotte L Edwardson, Danielle H Bodicoat, Dale W Esliger, Jason M R Gill, Aadil Kazi, Latha Velayudhan, Alan J Sinclair, Naveed Sattar and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Kishan BakraniaDepartment of Health Sciences, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Thomas YatesDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Charlotte L EdwardsonDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Danielle H BodicoatDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Dale W EsligerLifestyle and Physical Activity Biomedical Research Unit (BRU), National Institute for Health Research (NIHR) Leicester-Loughborough Diet, Diabetes Research Centre, Leicester General Hospital, Leicester, Leicestershire, UK.
Jason M R GillBritish Heart Foundation Glasgow Cardiovascular Research Centre (BHF GCRC), Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Aadil KaziDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Latha VelayudhanPsychiatry for the Elderly, Department of Health Sciences, University of Leicester, Leicester, Leicestershire, UK.
Alan J SinclairDiabetes Frail Ltd, Aston University, Birmingham, UK.
Naveed SattarBritish Heart Foundation Glasgow Cardiovascular Research Centre (BHF GCRC), Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Stuart J H BiddleInstitute of Sport, Exercise and Active Living, Victoria University, Melbourne, Victoria, Australia.
Mark HamerLifestyle and Physical Activity Biomedical Research Unit (BRU), National Institute for Health Research (NIHR) Leicester-Loughborough Diet, Diabetes Research Centre, Leicester General Hospital, Leicester, Leicestershire, UK.
Melanie J DaviesDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
Kamlesh KhuntiDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, Leicestershire, UK.
University of Leicester · GBLeicester General Hospital · GBNational Institute for Health Research · GBAston University · GBBritish Heart Foundation · GBNIHR Leicester Biomedical Research Centre · GBNIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit · GBOxleas NHS Foundation Trust · GBUniversity of Glasgow · GBVictoria University · AU

Funding

Department of Health [UK] MR/K025090/1Medical Research Council MR/K025090/1
6 · The paper itself

Abstract

objectivesTo investigate the associations of objectively measured moderate-to-vigorous-intensity physical activity (MVPA) and body mass index (BMI) with glycated haemoglobin (HbA1c) in a national sample of English adults.

methodsThe 2008 Health Survey for England data were used with 1109 participants aged ≥18 providing complete data. MVPA time was assessed using an accelerometer. Weighted linear regression models, adjusted for several confounders, quantified the associations between continuous measures of MVPA and BMI with HbA1c. Interaction analyses were implemented to observe whether the association of MVPA with HbA1c was modified by BMI or vice versa. Further weighted linear regression models examined the differences in HbA1c across four mutually exclusive categories of MVPA and BMI: (1) 'physically active and non-obese', (2) 'physically active and obese', (3) 'physically inactive and non-obese' and (4) 'physically inactive and obese'. 'Physically active' was defined as: ≥150 min/week of MVPA. 'Obese' was defined as: BMI ≥30.0 kg/m

resultsEvery 30 min/day increment in MVPA was associated with a 0.7 mmol/mol (0.07% (p<0.001)) lower HbA1c level. Each 1 kg/m

conclusionsThis study emphasises the importance of physical activity as a determinant of HbA1c, and suggests that the associations may be stronger in obese adults.

Indexed as

ExerciseAdultAgedBody Mass IndexCross-Sectional StudiesEnglandFemaleGlycated HemoglobinHealth SurveysHumansLinear ModelsMaleMiddle AgedObesityGlycated Hemoglobinhemoglobin A1c protein, humanBody Mass IndexEPIDEMIOLOGYGlycated HaemoglobinModerate-to-Vigorous-Intensity Physical ActivityObesityType 2 Diabetes Mellitus

Identifiers

PMID28373255
PMCPMC5387972
OpenAlexW2605202329

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.