Evidence map›Paper›PMID 28373203›Full record

ArticleThe Journal of cell biology2017

Three-tier regulation of cell number plasticity by neurotrophins and Tolls in

Istvan Foldi, Niki Anthoney, Neale Harrison, Monique Gangloff, Brett Verstak, Mohanakarthik Ponnadai Nallasivan, Samaher AlAhmed, Bangfu Zhu, Mark Phizacklea, Maria Losada-Perez and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

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  16. Review
  17. The Toll Route to Structural Brain Plasticity.Frontiers in physiology · 2021
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Istvan FoldiNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-1832-9854
Niki AnthoneyNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0003-3311-6328
Neale HarrisonNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0001-6821-4089
Monique GangloffDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1GA, England, UK.ORCID 0000-0001-6131-0115
Brett VerstakDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1GA, England, UK.ORCID 0000-0003-1459-114X
Mohanakarthik Ponnadai NallasivanNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-5244-5816
Samaher AlAhmedNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-3299-8157
Bangfu ZhuNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-9325-926X
Mark PhizackleaNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.
Maria Losada-PerezNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-6717-7762
Marta MoreiraNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK.ORCID 0000-0002-4779-4077
Nicholas J GayDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1GA, England, UK.
Alicia HidalgoNeuroDevelopment Group, School of Biosciences, University of Birmingham, Birmingham B15 2TT, England, UK a.hidalgo@bham.ac.uk.ORCID 0000-0001-8041-5764
University of Birmingham · GBUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L008343/1Medical Research Council
6 · The paper itself

Abstract

Cell number plasticity is coupled to circuitry in the nervous system, adjusting cell mass to functional requirements. In mammals, this is achieved by neurotrophin (NT) ligands, which promote cell survival via their Trk and p75

Indexed as

AnimalsCell CountCell DeathCell SurvivalDrosophilaNerve Growth FactorsNeuronal PlasticitySignal TransductionToll-Like ReceptorsNerve Growth FactorsToll-Like Receptors

Identifiers

PMID28373203
PMCPMC5412559
OpenAlexW2605232447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.