Evidence map›Paper›PMID 28373184›Full record

ArticleAntimicrobial agents and chemotherapy2017

9-(2'-Deoxy-2'-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance.

Farahnaz Ranjbarian, Munender Vodnala, Khalid J H Alzahrani, Godwin U Ebiloma, Harry P de Koning, Anders Hofer

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Drug resistance in animal trypanosomiases: Epidemiology, mechanisms and control strategies.International journal for parasitology. Drugs and drug resistance · 2024
    Review
  2. Nucleoside Transport and Nucleobase Uptake Null Mutants inInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Farahnaz RanjbarianDepartment of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden.
Munender VodnalaDepartment of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden.
Khalid J H AlzahraniInstitute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Godwin U EbilomaInstitute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Harry P de KoningInstitute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Anders HoferDepartment of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden anders.hofer@umu.se.
Umeå University · SEUniversity of Glasgow · GBTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current chemotherapy against African sleeping sickness, a disease caused by the protozoan parasite

Indexed as

AdenineAdenosine KinaseAnimalsAntimetabolitesDrug ResistanceMicePurine-Nucleoside PhosphorylaseTrypanosomaTrypanosoma brucei bruceiTrypanosomiasis, African5'-methylthioadenosine phosphorylaseAdenineAdenosine KinaseAntimetabolitesPurine-Nucleoside Phosphorylase9-(2′-deoxy-2′-fluoro-β-d-arabinofuranosyl) adenineadenosine kinasedrug resistanceFANA-Amethylthioadenosine phosphorylasenucleoside transportersTrypanosoma bruceitrypanosome

Identifiers

PMID28373184
PMCPMC5444181
OpenAlexW2604380330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.