Evidence map›Paper›PMID 28372982›Full record

ArticleDevelopmental cognitive neuroscience2018

Neural correlates of face processing in etiologically-distinct 12-month-old infants at high-risk of autism spectrum disorder.

Maggie W Guy, John E Richards, Bridgette L Tonnsen, Jane E Roberts

Erratum issuedAbstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Maggie W GuyDepartment of Psychology and Institute for Mind and Brain, University of South Carolina, United States. Electronic address: guymw@mailbox.sc.edu.
John E RichardsDepartment of Psychology and Institute for Mind and Brain, University of South Carolina, United States.
Bridgette L TonnsenDepartment of Psychology and Institute for Mind and Brain, University of South Carolina, United States.
Jane E RobertsDepartment of Psychology and Institute for Mind and Brain, University of South Carolina, United States.

Funding

Supplement to The Emergence and Stability of Autism in Fragile X SyndromeR01MH090194 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ROBERTS, JANE E · 2011 to 2020
$5.4M
The Development of Sustained Attention in InfantsR37HD018942 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 2007 to 2016
$4.5M
The development of sustained attention in infantsR01HD018942 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 1988 to 2021
$4.2M
The Neurodevelopmental MRI DatabaseR03HD091464 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 2017 to 2018
$128k
Predicting Autism through Behavioral and Biomarkers of Attention in InfantsF31MH095318 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KELLEHER, BRIDGETTE LYNNE · 2011 to 2014
$97k
NICHD NIH HHS R01 HD018942NICHD NIH HHS R03 HD091464NICHD NIH HHS R37 HD018942NIMH NIH HHS F31 MH095318NIMH NIH HHS R01 MH090194
6 · The paper itself

Abstract

Neural correlates of face processing were examined in 12-month-olds at high-risk for autism spectrum disorder (ASD), including 21 siblings of children with ASD (ASIBs) and 15 infants with fragile X syndrome (FXS), as well as 21 low-risk (LR) controls. Event-related potentials were recorded to familiar and novel face and toy stimuli. All infants demonstrated greater N290 amplitude to faces than toys. At the Nc component, LR infants showed greater amplitude to novel stimuli than to their mother's face and own toy, whereas infants with FXS showed the opposite pattern of responses and ASIBs did not differentiate based on familiarity. These results reflect developing face specialization across high- and low-risk infants and reveal neural patterns that distinguish between groups at high-risk for ASD.

Indexed as

Facial RecognitionRecognition, PsychologyAutism Spectrum DisorderEvoked PotentialsFemaleHumansInfantMaleRiskSiblingsAutism spectrum disordersEvent-related potentialsFace processingInfancy

Identifiers

PMID28372982
PMCPMC5600635

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.