Evidence map›Paper›PMID 28372097›Full record

ArticleThe Journal of the Acoustical Society of America2017

Automated setup for ex vivo larynx experiments.

Veronika Birk, Michael Döllinger, Alexander Sutor, David A Berry, Dominik Gedeon, Maximilian Traxdorf, Olaf Wendler, Christopher Bohr, Stefan Kniesburges

Abstract readVideo-Audio Media
In one paragraph

Article in The Journal of the Acoustical Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Functional Analysis of Injectable Substance Treatment on Surgically Injured Rabbit Vocal Folds.Journal of voice : official journal of the Voice Foundation · 2023
    Article
  5. Article
  6. Article
  7. Bioreactors for Vocal Fold Tissue Engineering.Tissue engineering. Part B, Reviews · 2022
    Review
  8. Article
  9. Fluid-structure-acoustic interactions in an ex vivo porcine phonation model.The Journal of the Acoustical Society of America · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Laryngeal Pressure Estimation With a Recurrent Neural Network.IEEE journal of translational engineering in health and medicine · 2019
    Article
  15. Investigation of phonatory characteristics using ex vivo rabbit larynges.The Journal of the Acoustical Society of America · 2018
    Article
  16. Influence of glottal closure on the phonatory process in ex vivo porcine larynges.The Journal of the Acoustical Society of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Veronika BirkMedical School, Division of Phoniatrics and Pediatric Audiology at the Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Raumerstrasse 1a, 91054 Erlangen, Germany.
Michael DöllingerMedical School, Division of Phoniatrics and Pediatric Audiology at the Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Raumerstrasse 1a, 91054 Erlangen, Germany.
Alexander SutorChair of Sensor Technology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Strasse 3/5, 91052 Erlangen, Germany.
David A BerryLaryngeal Dynamics Laboratory, Division of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, California 90095-1624, USA.
Dominik GedeonChair of Sensor Technology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Strasse 3/5, 91052 Erlangen, Germany.
Maximilian TraxdorfDepartment of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Waldstrasse 1, 91054 Erlangen, Germany.
Olaf WendlerLaboratory for Molecular Biology at the Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Waldstrasse 1, 91054 Erlangen, Germany.
Christopher BohrMedical School, Division of Phoniatrics and Pediatric Audiology at the Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Raumerstrasse 1a, 91054 Erlangen, Germany.
Stefan KniesburgesMedical School, Division of Phoniatrics and Pediatric Audiology at the Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Erlangen, Raumerstrasse 1a, 91054 Erlangen, Germany.

Funding

Mechanisms of Vocal RegistersR01DC013323 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BERRY, DAVID A · 2014 to 2018
$2.6M
NIDCD NIH HHS R01 DC013323
6 · The paper itself

Abstract

Ex vivo larynx experiments are limited in time due to degeneration of the laryngeal tissues. In order to acquire a significant and comparable amount of data, automatization of current manual experimental procedures is desirable. A computer controlled, electro-mechanical setup was developed for time-dependent variation of specific physiological parameters, including adduction and elongation level of the vocal folds and glottal flow. The setup offers a standardized method to induce defined forces on the laryngeal cartilages. Furthermore, phonation onset is detected automatically and the subsequent measurement procedure is automated and standardized to improve the efficiency of the experimental process. The setup was validated using four ex vivo porcine larynges, whereas each validation measurement series was executed with one separate larynx. Altogether 31 single measurements were undertaken, which can be summed up to a total experimental time of about 4 min. Vocal fold elongation and adduction lead both to an increase in fundamental frequency and subglottal pressure. Measurement procedures like applying defined subglottal pressure steps and onset-offset detection were reliably executed. The setup allows for a computer-based parameter control, which enables fast experimental execution over a wide range of laryngeal configurations. This maximizes the number of measurements and reduces personal effort compared with manual procedures.

Indexed as

LaryngectomyPhonationTransducers, PressureAnimalsAutomation, LaboratoryBiomechanical PhenomenaIn Vitro TechniquesLarynxModels, AnimalPressureReproducibility of ResultsSignal Processing, Computer-AssistedSus scrofaTime FactorsVideo Recording

Identifiers

PMID28372097
PMCPMC6909984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.