Evidence map›Paper›PMID 28371562›Full record

ArticleStem cells translational medicine2017

Amnion Epithelial Cells Promote Lung Repair via Lipoxin A

Jean L Tan, Yan Z Tan, Ruth Muljadi, Siow T Chan, Sin N Lau, Joanne C Mockler, Euan M Wallace, Rebecca Lim

Open access · goldAbstract read
In one paragraph

Article in Stem cells translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Extracellular Vesicles From Perinatal Cells for Anti-inflammatory Therapy.Frontiers in bioengineering and biotechnology · 2021
    Review
  10. Review
  11. Article
  12. Perinatal Cells: A Promising COVID-19 Therapy?Frontiers in bioengineering and biotechnology · 2020
    Review
  13. Review
  14. The effect of human amniotic epithelial cells on urethral stricture fibroblasts.Journal of clinical and translational research · 2019
    Article
  15. Article
  16. Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jean L TanThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Yan Z TanThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Ruth MuljadiThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Siow T ChanThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Sin N LauThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Joanne C MocklerThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Euan M WallaceThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Rebecca LimThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Hudson Institute of Medical Research · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human amnion epithelial cells (hAECs) have been shown to possess potent immunomodulatory properties across a number of disease models. Recently, we reported that hAECs influence macrophage polarization and activity, and that this step was dependent on regulatory T cells. In this study, we aimed to assess the effects of hAEC-derived proresolution lipoxin-A

Indexed as

AmnionAnimalsCell MovementCell ProliferationCells, CulturedCytokinesEpithelial CellsHumansInflammationLipoxinsLungMacrophagesMice, Inbred C57BLNeutrophilsPeroxidasePhagocytosisCytokineslipoxin A4LipoxinsPeroxidaseInflammationLipoxin A4Lung fibrosisMacrophagesNeutrophils

Identifiers

PMID28371562
PMCPMC5442827
OpenAlexW2552372800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.