Evidence map›Paper›PMID 28370663›Full record

ArticleProtein science : a publication of the Protein Society2017

Activation mechanisms of the first sphingosine-1-phosphate receptor.

Alisha D Caliman, Yinglong Miao, J Andrew McCammon

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Structural insights into sphingosine-1-phosphate receptor activation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alisha D CalimanDepartment of Pharmacology, University of California at San Diego, La Jolla, California, 92093.
Yinglong MiaoDepartment of Pharmacology, University of California at San Diego, La Jolla, California, 92093.
J Andrew McCammonDepartment of Pharmacology, University of California at San Diego, La Jolla, California, 92093.
Howard Hughes Medical Institute · USUniversity of California, San Diego · US

Funding

National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5M
THEORY OF BIOMOLECULAR DIFFUSIONR01GM031749 · NIGMS · UNIVERSITY OF HOUSTON · PI HUBER, GARY ALEXANDER, MCCAMMON, JAMES ANDREW · 1985 to 2022
$7.8M
Howard Hughes Medical InstituteNIGMS NIH HHS P41 GM103426NIGMS NIH HHS R01 GM031749NIGMS NIH HHS T32 GM007752
6 · The paper itself

Abstract

Activation of the first sphingosine-1-phosphate receptor (S1PR

Indexed as

Computer SimulationMolecular Dynamics SimulationHumansProtein Structure, SecondaryReceptors, LysosphingolipidSphingosine-1-Phosphate ReceptorsReceptors, LysosphingolipidS1PR1 protein, humanSphingosine-1-Phosphate ReceptorsactivationGPCRmolecular dynamicsS1PR1

Identifiers

PMID28370663
PMCPMC5441409
OpenAlexW2603879734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.