Evidence map›Paper›PMID 28370073›Full record

ReviewElectrophoresis2017

Characterization of isomeric glycan structures by LC-MS/MS.

Lucas Veillon, Yifan Huang, Wenjing Peng, Xue Dong, Byeong Gwan Cho, Yehia Mechref

Open access · greenAbstract readReview
In one paragraph

Review in Electrophoresis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 160 citations in OpenAlex.

  1. PredictiveACS omega · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. SerumACS omega · 2024
    Article
  15. Article
  16. Article
  17. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
  18. Review
  19. Article
  20. Journal of proteome research · 2024
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lucas VeillonDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Yifan HuangDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Wenjing PengDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Xue DongDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Byeong Gwan ChoDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.
Texas Tech University · US

Funding

Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
NIGMS NIH HHS R01 GM112490
6 · The paper itself

Abstract

The characterization of glycosylation is critical for obtaining a comprehensive view of the regulation and functions of glycoproteins of interest. Due to the complex nature of oligosaccharides, stemming from variable compositions and linkages, and ion suppression effects, the chromatographic separation of glycans, including isomeric structures, is necessary for exhaustive characterization by MS. This review introduces the fundamental principles underlying the techniques in LC utilized by modern day glycomics researchers. Recent advances in porous graphitized carbon, reverse phase, ion exchange, and hydrophilic interaction LC utilized in conjunction with MS, for the characterization of protein glycosylation, are described with an emphasis on methods capable of resolving isomeric glycan structures.

Indexed as

Chromatography, LiquidIsomerismPolysaccharidesTandem Mass SpectrometryPolysaccharidesGlycan analysisIsomeric separationLC-MS/MSLiquid chromatographyMass spectrometry

Identifiers

PMID28370073
PMCPMC5581235
OpenAlexW2597467486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.