Evidence map›Paper›PMID 28369667›Full record

ArticleCurrent protocols in protein science2017

Measuring Protein Interactions by Optical Biosensors.

Huaying Zhao, Lisa F Boyd, Peter Schuck

Abstract read
In one paragraph

Article in Current protocols in protein science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huaying ZhaoNational Institutes of Health, Bethesda, Maryland.
Lisa F BoydNational Institutes of Health, Bethesda, Maryland.
Peter SchuckNational Institutes of Health, Bethesda, Maryland.

Funding

Multi-Method Approaches for the Study of Complex Protein InteractionsZIAEB000050 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI SCHUCK, PETER · 2009 to 2025
$1.7M
Development of Biosensor Technology for Protein InteractionsZ01EB000049 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI SCHUCK, PETER · 2007 to 2008
$79k
Intramural NIH HHS Z01 EB000049
6 · The paper itself

Abstract

This unit gives an introduction to the basic techniques of optical biosensing for measuring equilibrium and kinetics of reversible protein interactions. Emphasis is placed on description of robust approaches that will provide reliable results with few assumptions. How to avoid the most commonly encountered problems and artifacts is also discussed. © 2017 by John Wiley & Sons, Inc.

Indexed as

Biosensing TechniquesKineticsMolecular StructureOptical DevicesProtein BindingProtein Interaction MappingProteinsReproducibility of ResultsSurface PropertiesThermodynamicsProteinsbiolayer interferometryoptical biosensorprotein interactionssurface plasmon resonance

Identifiers

PMID28369667
PMCPMC5776739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.