SynthesisSchizophrenia bulletin2018
Loneliness in Psychosis: A Meta-analytical Review.
Synthesis in Schizophrenia bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 9 syntheses or guidelines pooled it, 294 citations in OpenAlex.
- Prevalence of loneliness and social isolation amongst individuals with severe mental disorders: a systematic review and meta-analysis.Epidemiology and psychiatric sciences · 2025Pooled it
- The experience of loneliness among people with psychosis: Qualitative meta-synthesis.PloS one · 2024Pooled it
- Associations between constructs related to social relationships and mental health conditions and symptoms: an umbrella review.BMC psychiatry · 2023Pooled it
- Loneliness and the onset of new mental health problems in the general population.Social psychiatry and psychiatric epidemiology · 2022Pooled it
- Pooled it
- Periodontal Disease and Age-Related Macular Degeneration: A Meta-Analysis of 112,240 Participants.BioMed research international · 2020Pooled it
- Shedding Light on "the Hole": A Systematic Review and Meta-Analysis on Adverse Psychological Effects and Mortality Following Solitary Confinement in Correctional Settings.Frontiers in psychiatry · 2020Pooled it
- Potential Benefits of Incorporating Peer-to-Peer Interactions Into Digital Interventions for Psychotic Disorders: A Systematic Review.Psychiatric services (Washington, D.C.) · 2018Pooled it
- Loneliness in psychosis: a systematic review.Social psychiatry and psychiatric epidemiology · 2018Pooled it
- Long-term outcomes of assertive community treatment in Japan: 7-year follow-up of a randomized controlled trial.BMC psychiatry · 2025Trial
- Experiences of friendships of young people with first-episode psychosis: A qualitative study.PloS one · 2021Trial
- Relationships between smartphone social behavior and relapse in schizophrenia: A preliminary report.Schizophrenia research · 2019Trial
- External validation and refinement of the Psychosis Polyrisk Score to detect individuals at clinical high risk for psychosis.BMJ mental health · 2026Observational
- Prevalence of social disconnection in the general adult population - results from DISCONNECT study.Social psychiatry and psychiatric epidemiology · 2026Article
- Using smartphone-based assessment of social experience to predict relapse in first-episode psychosis.Schizophrenia (Heidelberg, Germany) · 2026Article
- Loneliness in Schizophrenia: The Mediating Roles of Asocial Beliefs and Mattering.The International journal of social psychiatry · 2026Article
- Community severance and mental health-related hospital visits in New York City.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Social disconnection and psychotic-like experiences in the Slovak DISCONNECT epidemiological study.Scientific reports · 2026Article
- Social functioning, loneliness, and psychosis phenotype in the general population: a network analysis perspective.Social psychiatry and psychiatric epidemiology · 2026Article
- Linking peripheral low-grade inflammation and blood-cerebrospinal fluid barrier leakage in schizophrenia spectrum disorders - A retrospective analysis.Brain, behavior, & immunity - health · 2026Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loneliness may be related to psychotic symptoms but a comprehensive synthesis of the literature in this area is lacking. The primary aim of the current study is to provide a systematic review and meta-analysis of the association between loneliness and psychotic symptoms in people with psychosis. A search of electronic databases was conducted (PsychINFO, MEDLINE, EMBASE, and Web of Science). A random effects meta-analysis was used to compute a pooled estimate of the correlation between loneliness and psychotic symptoms. Study and outcome quality were assessed using adapted versions of the Agency for Healthcare Research and Quality (AHRQ) tool and GRADE approach, respectively. Thirteen studies were included, providing data from 15 647 participants. A moderate association between psychosis and loneliness was observed (k = 13, N = 15 647, r = .32, 95% CI 0.20, 0.44; I2 = 97.56%; moderate quality evidence). Whether loneliness was assessed by a single-item or a more comprehensive measure had no moderating effect on the estimate. Results indicate that there is a significant positive relationship between loneliness and psychosis. Further studies are needed to determine the causal status of this relationship, but this robust finding should be considered in clinical practice and treatment provision for those with psychotic disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.