Evidence map›Paper›PMID 28369515›Full record

ReviewILAR journal2017

Tick-Borne Zoonoses in the United States: Persistent and Emerging Threats to Human Health.

Rebecca J Eisen, Kiersten J Kugeler, Lars Eisen, Charles B Beard, Christopher D Paddock

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ILAR journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 171 papers.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 319 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Acquired tick resistance inInfection and immunity · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rebecca J EisenRebecca J. Eisen, PhD, is a Research Biologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Kiersten J. Kugeler, PhD, is an Epidemiologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Lars Eisen, PhD, is a Research Entomologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Charles B. Beard, PhD, is a Branch Chief in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Christopher D. Paddock, MD, is a Medical Officer/Pathologist in the Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Atlanta, Georgia.
Kiersten J KugelerRebecca J. Eisen, PhD, is a Research Biologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Kiersten J. Kugeler, PhD, is an Epidemiologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Lars Eisen, PhD, is a Research Entomologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Charles B. Beard, PhD, is a Branch Chief in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Christopher D. Paddock, MD, is a Medical Officer/Pathologist in the Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Atlanta, Georgia.
Lars EisenRebecca J. Eisen, PhD, is a Research Biologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Kiersten J. Kugeler, PhD, is an Epidemiologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Lars Eisen, PhD, is a Research Entomologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Charles B. Beard, PhD, is a Branch Chief in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Christopher D. Paddock, MD, is a Medical Officer/Pathologist in the Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Atlanta, Georgia.
Charles B BeardRebecca J. Eisen, PhD, is a Research Biologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Kiersten J. Kugeler, PhD, is an Epidemiologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Lars Eisen, PhD, is a Research Entomologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Charles B. Beard, PhD, is a Branch Chief in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Christopher D. Paddock, MD, is a Medical Officer/Pathologist in the Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Atlanta, Georgia.
Christopher D PaddockRebecca J. Eisen, PhD, is a Research Biologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Kiersten J. Kugeler, PhD, is an Epidemiologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Lars Eisen, PhD, is a Research Entomologist in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Charles B. Beard, PhD, is a Branch Chief in the Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Fort Collins, Colorado. Christopher D. Paddock, MD, is a Medical Officer/Pathologist in the Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention in Atlanta, Georgia.
Centers for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

In the United States, ticks transmit the greatest diversity of arthropod-borne pathogens and are responsible for the most cases of all vector-borne diseases. In recent decades, the number of reported cases of notifiable tick-borne diseases has steadily increased, geographic distributions of many ticks and tick-borne diseases have expanded, and new tick-borne disease agents have been recognized. In this review, we (1) describe the known disease agents associated with the most commonly human-biting ixodid ticks, (2) review the natural histories of these ticks and their associated pathogens, (3) highlight spatial and temporal changes in vector tick distributions and tick-borne disease occurrence in recent decades, and (4) identify knowledge gaps and barriers to more effective prevention of tick-borne diseases. We describe 12 major tick-borne diseases caused by 15 distinct disease agents that are transmitted by the 8 most commonly human-biting ixodid ticks in the United States. Notably, 40% of these pathogens were described within the last two decades. Our assessment highlights the importance of animal studies to elucidate how tick-borne pathogens are maintained in nature, as well as advances in molecular detection of pathogens which has led to the discovery of several new tick-borne disease agents.

Indexed as

AnimalsHumansTick-Borne DiseasesTicksUnited StatesZoonoses

Identifiers

PMID28369515
PMCPMC5610605
OpenAlexW2600291485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.