Evidence map›Paper›PMID 28369362›Full record

ArticleEuropean heart journal2017

Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study.

Tinne Tranberg, Freddy K Lippert, Erika F Christensen, Carsten Stengaard, Jakob Hjort, Jens Flensted Lassen, Frants Petersen, Jan Skov Jensen, Caroline Bäck, Lisette Okkels Jensen and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in European heart journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Tinne TranbergDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Freddy K LippertPrehospital Emergency Medical Services, The Capital Region of Denmark.
Erika F ChristensenPrehospital Emergency Medical Services, The North Denmark Region, Aalborg.
Carsten StengaardDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Jakob HjortDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Jens Flensted LassenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Frants PetersenThe Heart Centre, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Jan Skov JensenDepartment of Cardiology, Gentofte Hospital, Copenhagen, Denmark.
Caroline BäckDepartment of Cardiothoracic Surgery, Copenhagen University Hospital, Copenhagen, Denmark.
Lisette Okkels JensenDepartment of Cardiology, Odense University Hospital, Odense, Denmark.
Jan RavkildeDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Hans Erik BøtkerDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Christian Juhl TerkelsenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8280 Aarhus N, Denmark.
Aarhus University Hospital · DKAalborg University Hospital · DKCopenhagen University Hospital · DKCapital Region of Denmark · DKGentofte Hospital · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients. METHODS AND

resultsNationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.

conclusionAdmission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.

Indexed as

Cardiopulmonary ResuscitationCoronary AngiographyCoronary Care UnitsCritical CareDenmarkEmergency Service, HospitalFemaleFollow-Up StudiesHospitalizationHumansMaleOut-of-Hospital Cardiac ArrestPercutaneous Coronary InterventionResidence CharacteristicsST Elevation Myocardial InfarctionTime-to-Treatment30-day survivalAcute CAG/PCIDistance from the site of arrest to invasive heart centreHospital-level-of-careOut-of-hospital cardiac arrestPopulation density

Identifiers

PMID28369362
PMCPMC5451896
OpenAlexW2598395923

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.