Evidence map›Paper›PMID 28369214›Full record

ArticleBioinformatics (Oxford, England)2017

Constructing linkage maps in the genomics era with MapDisto 2.0.

Christopher Heffelfinger, Christopher A Fragoso, Mathias Lorieux

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A candidate gene marker at the red kidney color locus (Rk) enables the development of slow-darkening pink beans.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  3. Global perspective on the genetic architecture of susceptibility to spot form net blotch in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  6. Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
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  13. Host and pathogen genetics reveal an inverse gene-for-gene association in the P. teres f. maculata-barley pathosystem.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
  14. Haplotype variants of Sr46 in Aegilops tauschii, the diploid D genome progenitor of wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher HeffelfingerDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.
Christopher A FragosoDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA.
Mathias LorieuxDIADE Research Unit, Institut de Recherche pour le Développement (IRD), Montpellier, France.

Funding

MEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2M
YALE BIOMEDICAL SUPERCOMPUTER: NEUROSCIENCES10RR019895 · NCRR · YALE UNIVERSITY · PI WILLIAMS, KENNETH ROBERT · 2004 to 2004
$1.6M
High Performance Computing Instrumentation for Yale University Biomedical HPC CenS10RR029676 · NCRR · YALE UNIVERSITY · PI BJORNSON, ROBERT DEAN · 2011 to 2011
$588k
NCRR NIH HHS S10 RR019895NCRR NIH HHS S10 RR029676NLM NIH HHS T15 LM007056
6 · The paper itself

Abstract

motivationGenotyping by sequencing (GBS) generates datasets that are challenging to handle by current genetic mapping software with graphical interface. Geneticists need new user-friendly computer programs that can analyze GBS data on desktop computers. This requires improvements in computation efficiency, both in terms of speed and use of random-access memory (RAM).

resultsMapDisto v.2.0 is a user-friendly computer program for construction of genetic linkage maps. It includes several new major features: (i) handling of very large genotyping datasets like the ones generated by GBS; (ii) direct importation and conversion of Variant Call Format (VCF) files; (iii) detection of linkage, i.e. construction of linkage groups in case of segregation distortion; (iv) data imputation on VCF files using a new approach, called LB-Impute. Features i to iv operate through inclusion of new Java modules that are used transparently by MapDisto; (v) QTL detection via a new R/qtl graphical interface. AVAILABILITY AND IMPLEMENTATION: The program is available free of charge at mapdisto.free.fr. CONTACT: mapdisto@gmail.com. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Genetic LinkageSoftwareChromosome MappingGenomicsGenotyping TechniquesSequence Analysis, DNA

Identifiers

PMID28369214
PMCPMC5870660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.