Evidence map›Paper›PMID 28369190›Full record

ArticleAmerican journal of hypertension2017

Physical Activity Is Associated With Reduced Left Ventricular Mass in Obese and Hypertensive African Americans.

Daisuke Kamimura, Paul D Loprinzi, Wanmei Wang, Takeki Suzuki, Kenneth R Butler, Thomas H Mosley, Michael E Hall

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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  7. Article
  8. Review
  9. Neurocirculatory regulation and adaptations to exercise in chronic kidney disease.American journal of physiology. Heart and circulatory physiology · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daisuke KamimuraDivision of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Paul D LoprinziCenter for Health Behavior Research, University of Mississippi, University, Mississippi, USA.
Wanmei WangCenter of Biostatistics & Bioinformatics, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Takeki SuzukiDivision of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Kenneth R ButlerDivision of Geriatrics and Gerontology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Thomas H MosleyDivision of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Michael E HallDivision of Cardiology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
University of Mississippi Medical Center · USUniversity of Mississippi · US

Funding

GENETIC DETERMINANTS OF HIGH BLOOD PRESSURE (GENOA)U01HL054463 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI MOSLEY, THOMAS H · 2000 to 2004
$1.6M
Renal Sinus Fat, Hypertension, and Altered Kidney FunctionK08DK099415 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, MICHAEL EDWARD · 2015 to 2019
$791k
NHLBI NIH HHS U01 HL054463NIDDK NIH HHS K08 DK099415
6 · The paper itself

Abstract

backgroundPhysical activity (PA) has been associated with decreased left ventricular (LV) hypertrophy in previous studies. However, little is known about the relationship between PA and LV structure and factors which influence this relationship among African Americans.

methodsWe evaluated 1,300 African Americans with preserved LV ejection fraction (EF > 50%) from the Genetic Epidemiology Network of Arteriopathy (GENOA) Study (mean age 62.4 years, 73% women). PA index was calculated as 3 * heavy activity hours + 2 * moderate activity hours + slight activity hours/day. The relationship between PA index and LV structure was evaluated using generalized estimating equation. The association between PA index and LV mass index by age group, sex, body mass index (BMI), history of hypertension, diabetes or coronary heart disease, estimated glomerular filtration rate, and current smoking status were plotted.

resultsAfter adjustment for these factors, higher PA index was independently associated with lower LV mass index (P < 0.05). There were significant interactions between PA index and obesity (BMI ≥ 30) and history of hypertension on LV mass index (P for interaction <0.05, for both). Higher PA index was associated with lower LV mass index more in obese or hypertensive participants compared with nonobese or nonhypertensive participants.

conclusionsHigher PA index was associated with reduced LV hypertrophy in obese and hypertensive African Americans. Prospective studies aimed at assessing whether increasing PA prevents LV hypertrophy and potentially reduces the risk of heart failure in these at risk groups are warranted.

Indexed as

Black or African AmericanExerciseVentricular RemodelingAgedBlood PressureCross-Sectional StudiesFemaleHealth StatusHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedMississippiObesityPrognosisblood pressurehypertensionLV hypertrophyLV mass indexphysical activity.

Identifiers

PMID28369190
PMCPMC5861530
OpenAlexW2598207226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.