Evidence map›Paper›PMID 28368603›Full record

ArticleThe journal of physical chemistry. B2017

Hidden Mode of Action of Glycopeptide Antibiotics: Inhibition of Wall Teichoic Acid Biosynthesis.

Manmilan Singh, James Chang, Lauryn Coffman, Sung Joon Kim

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Screening of vancomycin resistance-associated genes in methicillin-resistantVeterinary research forum : an international quarterly journal · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. The Staphylococcal Cell Wall.Microbiology spectrum · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Manmilan SinghDepartment of Chemistry, Washington University , St. Louis, Missouri 63130, United States.
James ChangDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.
Lauryn CoffmanDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.
Sung Joon KimDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.ORCID 0000-0002-2007-6606
Baylor University · USWashington University in St. Louis · US

Funding

GLYCOPEPTIDE COMPLEXES WITH BACTERIAL CELL WALLS BY REDORR01GM116130 · NIGMS · WASHINGTON UNIVERSITY · PI PATTI, GARY J · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM116130
6 · The paper itself

Abstract

Glycopeptide antibiotics inhibit the peptidoglycan biosynthesis in Gram-positive bacteria by targeting lipid II. This prevents the recycling of bactoprenol phosphate, the lipid transporter that is shared by peptidoglycan and wall teichoic acid biosyntheses. In this study, we investigate the effects of glycopeptide antibiotics on peptidoglycan and wall teichoic acid biosynthesis. The incorporation of d-[1-

Indexed as

AlanineAnti-Bacterial AgentsBiosynthetic PathwaysCell WallGlycopeptidesHumansLipoglycopeptidesStaphylococcal InfectionsStaphylococcus aureusTeichoic AcidsVancomycinAlanineAnti-Bacterial AgentsGlycopeptidesLipoglycopeptidesoritavancinTeichoic AcidsVancomycin

Identifiers

PMID28368603
PMCPMC6013045
OpenAlexW2605207782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.