ArticleThe Journal of clinical endocrinology and metabolism2017
Risk of Thyroid Nodules in Residents of Belarus Exposed to Chernobyl Fallout as Children and Adolescents.
Article in The Journal of clinical endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07612735 (Impact of Strength Training on Mental Health and Physical Fitness in Women With Functional Hypothalamic Amenorrhea), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Strength Training on Mental Health and Physical Fitness in Women With Functional Hypothalamic Amenorrhea
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Somatic health effects of Chernobyl: 30 years on.European journal of epidemiology · 2017Pooled it
- Effects of explanatory information on parental intentions regarding child participation in thyroid ultrasound examinations after the Fukushima nuclear power plant accident: a questionnaire survey.Endocrine journal · 2026Article
- High prevalence of thyroid nodules and their association with cardiometabolic risk in Mongolia.Frontiers in cardiovascular medicine · 2026Article
- Validation of established thyroid ultrasound volume norms in a Chernobyl cohort.European thyroid journal · 2025Article
- Elemental comparative analysis of 18 elements reveal distinct patterns in benign and malignant thyroid tissues.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Prevalence of Thyroid Nodules in Residents of Ukraine Exposed as Children or Adolescents to Iodine-131 from the Chornobyl Accident.Thyroid : official journal of the American Thyroid Association · 2024Article
- Evaluation of the Performance of ACR TI-RADS Also Considering Those Nodules with No Indication of FNAC: A Single-Center Experience.Journal of clinical medicine · 2023Article
- Increased trend of thyroid cancer in childhood over the last 30 years in EU countries: a call for the pediatric surgeon.European journal of pediatrics · 2022Observational
- Epidemiology of Thyroid Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Modulation of Secondary Cancer Risks from Radiation Exposure by Sex, Age and Gonadal Hormone Status: Progress, Opportunities and Challenges.Journal of personalized medicine · 2022Review
- Molecular profiling of papillary thyroid carcinomas in healthcare workers exposed to low dose radiation at the workplace.Endocrine · 2022Article
- Age-related long-term response in rat thyroid tissue and plasma after internal low dose exposure toScientific reports · 2022Article
- Review of the risk of cancer following low and moderate doses of sparsely ionising radiation received in early life in groups with individually estimated doses.Environment international · 2022Review
- Association between exposure to radioactive iodine after the Chernobyl accident and thyroid volume in Belarus 10-15 years later.Environmental health : a global access science source · 2022Article
- Analysis of the influencing factors on fine-needle aspiration biopsy results of the thyroid.Frontiers in surgery · 2022Article
- Risk of thyroid cancer in Ukrainian cleanup workers following the Chornobyl accident.European journal of epidemiology · 2022Article
- Risk of Benign and Malignant Thyroid Disorders in Subjects Treated for Paediatric/Adolescent Neoplasia: Role of Morphological and Functional Screening.Children (Basel, Switzerland) · 2021Article
- Reliability of thyroid doses due toRadiation and environmental biophysics · 2021Article
- Consequences of atmospheric contamination by radioiodine: the Chernobyl and Fukushima accidents.Endocrine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 2 countries.
Funding
Abstract
Context: Although radiation exposure is an important predictor of thyroid cancer on diagnosis of a thyroid nodule, the relationship between childhood radiation exposure and thyroid nodules has not been comprehensively evaluated. Objective: To examine the association between internal I-131 thyroid dose and thyroid nodules in young adults exposed during childhood. Design, setting, and participants: In this cross-sectional study, we screened residents of Belarus aged ≤18 years at the time of the Chernobyl nuclear accident for thyroid disease (median age, 21 years) with thyroid palpation, ultrasonography, blood/urine analysis, and medical follow-up when appropriate. Eligible participants (N = 11,421) had intact thyroid glands and doses based on direct individual thyroid activity measurements. Main outcome measures: Excess odds ratios per Gray (EOR/Gy, scaled at age 5 years at exposure) for any thyroid nodule and for nodules grouped by cytology/histology, diameter size, and singularity. Results: Risk of any thyroid nodule increased significantly with I-131 dose and, for a given dose, with younger age at exposure. The EOR/Gy (95% confidence intervals) for neoplastic nodules (3.82; 0.87 to 15.52) was significantly higher than for nonneoplastic nodules (0.32; <0.03 to 0.70) and did not vary by size; whereas the EOR/Gy for nonneoplastic nodules did vary by size (P = 0.02) and was 1.55 (0.36 to 5.46) for nodules ≥10 mm and 0.02 (<-0.02 to 0.70) for nodules <10 mm. EORs/Gy for single and multiple nodules were comparable. Conclusions: Childhood exposure to internal I-131 is associated with increased risk of neoplastic thyroid nodules of any size and nonneoplastic nodules ≥10 mm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.