Evidence map›Paper›PMID 28368282›Full record

ArticleActa crystallographica. Section F, Structural biology communications2017

Crystal structure of enolase from Drosophila melanogaster.

Congcong Sun, Baokui Xu, Xueyan Liu, Zhen Zhang, Zhongliang Su

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. The βScientific reports · 2021
    Article
  4. Article
  5. Featured Species-Specific Loops Are Found in the Crystal Structure ofFrontiers in cellular and infection microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Congcong SunCollege of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, Shandong 266042, People's Republic of China.
Baokui XuJianghuai College, Anhui University, Hefei, Anhui 230039, People's Republic of China.
Xueyan LiuCollege of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, Shandong 266042, People's Republic of China.
Zhen ZhangLaboratory for TCM Immunopharmacology and Molecular Biology, Institute of Basic Medicine, Shandong Academy of Medical Sciences, 18877 Jingshi Road, Jinan, Shandong 250062, People's Republic of China.
Zhongliang SuCollege of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, Shandong 266042, People's Republic of China.

Funding

National Natural Science Foundation of China 81601442
6 · The paper itself

Abstract

Enolase is an important enzyme in glycolysis and various biological processes. Its dysfunction is closely associated with diseases. Here, the enolase from Drosophila melanogaster (DmENO) was purified and crystallized. A crystal of DmENO diffracted to 2.0 Å resolution and belonged to space group R32. The structure was solved by molecular replacement. Like most enolases, DmENO forms a homodimer with conserved residues in the dimer interface. DmENO possesses an open conformation in this structure and contains conserved elements for catalytic activity. This work provides a structural basis for further functional and evolutionary studies of enolase.

Indexed as

Amino Acid SequenceAnimalsCatalytic DomainCloning, MolecularConserved SequenceCrystallography, X-RayDrosophila melanogasterDrosophila ProteinsEscherichia coliGene ExpressionGenetic VectorsGlyceric AcidsModels, MolecularPhosphopyruvate HydrataseProtein BindingProtein Conformation, alpha-Helical2-phosphoglycerateDrosophila ProteinsGlyceric AcidsPhosphopyruvate HydrataseRecombinant Proteinsactive sitecrystal structuredimerizationDrosophila melanogasterenolaseglycolysis

Identifiers

PMID28368282
PMCPMC5379173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.