Evidence map›Paper›PMID 28368037›Full record

ArticleScientific reports2017

High-resolution RNA allelotyping along the inactive X chromosome: evidence of RNA polymerase III in regulating chromatin configuration.

Ru Hong, Bingqing Lin, Xinyi Lu, Lan-Tian Lai, Xin Chen, Amartya Sanyal, Huck-Hui Ng, Kun Zhang, Li-Feng Zhang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gene regulation in time and space during X-chromosome inactivation.Nature reviews. Molecular cell biology · 2022
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ru HongSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore.
Bingqing LinSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore.
Xinyi LuGenome Institute of Singapore, 138672, Singapore.
Lan-Tian LaiSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore.
Xin ChenDivision of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link 637371, Singapore.
Amartya SanyalSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore.
Huck-Hui NgGenome Institute of Singapore, 138672, Singapore.
Kun ZhangDepartment of Bioengineering, University of California at San Diego, La Jolla, CA 92093, USA.
Li-Feng ZhangSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore.
Nanyang Technological University · SGGenome Institute of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We carried out padlock capture, a high-resolution RNA allelotyping method, to study X chromosome inactivation (XCI). We examined the gene reactivation pattern along the inactive X (Xi), after Xist (X-inactive specific transcript), a prototype long non-coding RNA essential for establishing X chromosome inactivation (XCI) in early embryos, is conditionally deleted from Xi in somatic cells (Xi

Indexed as

AllelesAnimalsCell LineChromatinDatabases, GeneticGenes, X-LinkedMicePolymorphism, Single NucleotideRNA InterferenceRNA, Long NoncodingRNA Polymerase IIIRNA, Small InterferingTranscription Factors, TFIIITranscription Factor TFIIICX ChromosomeChromatinRNA, Long NoncodingRNA Polymerase IIIRNA, Small InterferingTranscription Factors, TFIIITranscription Factor TFIIICXIST non-coding RNA

Identifiers

PMID28368037
PMCPMC5377358
OpenAlexW2605095988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.