ArticleNucleic acids research1988
cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms.
Article in Nucleic acids research, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 107 citations in OpenAlex.
- Novel oligosaccharide has suppressive activity against human leukemia cell proliferation.Glycoconjugate journal · 2009Article
- Inserting a nuclear targeting signal into a replication-competent Moloney murine leukemia virus affects viral export and is not sufficient for cell cycle-independent infection.Journal of virology · 2002Article
- Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus.The EMBO journal · 2000Article
- The hrp23 protein in the balbiani ring pre-mRNP particles is released just before or at the binding of the particles to the nuclear pore complex.The Journal of cell biology · 1998Article
- Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.RNA (New York, N.Y.) · 1998Article
- Growth-dependent and growth-independent translation of messengers for heterogeneous nuclear ribonucleoproteins.Nucleic acids research · 1997Article
- Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3.Genetics · 1996Article
- Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.Journal of virology · 1995Article
- A nuclear localization domain in the hnRNP A1 protein.The Journal of cell biology · 1995Article
- Late induction of human DNA ligase I after UV-C irradiation.Nucleic acids research · 1995Article
- Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27.Journal of virology · 1995Article
- Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.The EMBO journal · 1994Article
- Characterization of a cDNA encoding a novel type of RNA-binding protein in tobacco: its expression and nucleic acid-binding properties.Molecular & general genetics : MGG · 1994Article
- Two homologous genes, originated by duplication, encode the human hnRNP proteins A2 and A1.Nucleic acids research · 1994Article
- RNP1, a new ribonucleoprotein gene of the yeast Saccharomyces cerevisiae.Nucleic acids research · 1994Article
- The C-protein tetramer binds 230 to 240 nucleotides of pre-mRNA and nucleates the assembly of 40S heterogeneous nuclear ribonucleoprotein particles.Molecular and cellular biology · 1994Article
- Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes.Human genetics · 1994Article
- Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1.Molecular and cellular biology · 1993Article
- hnRNP G: sequence and characterization of a glycosylated RNA-binding protein.Nucleic acids research · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein A1 is one of the major component of mammalian ribonucleoprotein particles (hnRNP). Human protein A1 cDNA cloning and sequencing revealed the existence of at least two protein isoforms. Among the cDNAs examined, sequence differences were found both in the structural portion, leading to aminoacid changes (Tyr to Phe or Arg to Lys) and in the non translated 3'-region where two T-stretches of different length were observed. Interestingly one of the aminoacid substitutions falls into a consensus sequence common to many RNA binding proteins. Northern blot analysis of poly A+ RNAs from five human tissues revealed two mRNA forms of 1500 and 1900 n due to alternative polyadenylation. Analysis of genomic DNA showed at least 30 A1-specific sequences, some of which correspond to processed pseudogenes. These results suggest that protein A1 is encoded by a multigene family.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.