ArticleScientific reports2017
B-vitamin Supplementation Mitigates Effects of Fine Particles on Cardiac Autonomic Dysfunction and Inflammation: A Pilot Human Intervention Trial.
Registry-linked trialOpen access · goldAbstract readControlled Clinical Trial
In one paragraph
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01864824 (Air Pollution, Epigenetics and Cardiovascular Health), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Air Pollution, Epigenetics and Cardiovascular Health: A Human Intervention Trial
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Effects of controlled, acute exposure to air pollutants on heart rate variability in humans: a meta-regression and methodological recommendations.BMC public health · 2026Pooled it
- Dietary supplementations to mitigate the cardiopulmonary effects of air pollution toxicity: A systematic review of clinical trials.PloS one · 2024Pooled it
- Trial
- Consumption of antioxidant-rich foods attenuates respiratory and cardiovascular health effects in a population highly exposed to air pollution.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Sex-Specific Heart Rate Variability Associations With Vitamin B12, Folate, and Iron Status.Reviews in cardiovascular medicine · 2026Article
- [Mitigating the Health Effects of Particulate Matter: A Narrative Review of Intervention Studies].Jugan geon-gang gwa jilbyeong · 2025Review
- The effects of vitamin B and D supplementations on autonomic functions and quality of life in children after vasovagal syncope.Frontiers in pediatrics · 2025Article
- Heart rate variability and its modulation by nutrients: a narrative review on implications for cardiovascular aging.Frontiers in neuroscience · 2025Review
- Fine particulate matter-sudden death association modified by ventricular hypertrophy and inflammation: a case-crossover study.Frontiers in public health · 2024Article
- A Narrative Review on the Impact of Air Pollution on Heart Failure Risk and Exacerbation.The Canadian journal of cardiology · 2023Review
- Association of fine particulate matter and its constituents with hypertension: the modifying effect of dietary patterns.Environmental health : a global access science source · 2023Article
- [Trends in Intervention Research for Reducing Health Effects of Particulate Matter].Jugan geon-gang gwa jilbyeong · 2023Review
- A Review of theInternational journal of genomics · 2023Review
- Cellular mechanisms linking to outdoor and indoor air pollution damage during pregnancy.Frontiers in endocrinology · 2023Review
- Environment and cardiovascular health: causes, consequences and opportunities in prevention and treatment.Revista espanola de cardiologia (English ed.) · 2022Review
- [Environment and cardiovascular health: causes, consequences and opportunities in prevention and treatment].Revista espanola de cardiologia · 2022Article
- Adverse effects of air pollution-derived fine particulate matter on cardiovascular homeostasis and disease.Trends in cardiovascular medicine · 2022Review
- Demonstrating the Applicability of Smartwatches in PMSensors (Basel, Switzerland) · 2021Article
- Fish oil and olive oil-enriched diets alleviate acute ozone-induced cardiovascular effects in rats.Toxicology and applied pharmacology · 2020Article
- Circulatory and Urinary B-Vitamin Responses to Multivitamin Supplement Ingestion Differ between Older and Younger Adults.Nutrients · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 7 institutions in 4 countries.
Jia ZhongColumbia University Mailman School of Public Health, New York, New York, USA.
Letizia TrevisiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Bruce UrchDivision of Occupational &Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Xinyi LinSingapore Institute for Clinical Sciences, Singapore.
Mary SpeckDivision of Occupational &Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Gary LissDivision of Occupational &Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Aaron ThompsonDivision of Occupational &Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Shaowei WuDepartment of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing, 100191 China.
Ander WilsonDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Frances SilvermanDivision of Occupational &Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Andrea A BaccarelliColumbia University Mailman School of Public Health, New York, New York, USA.
Harvard University · USColumbia University · USPublic Health Ontario · CAUniversity of Toronto · CAPeking University · CNSingapore Institute for Clinical Sciences · SGSt. Michael's Hospital · CA
Funding
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7MTranslational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6MGRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9MBPA, Phthalates & Stress: Mechanisms and Interactions for Childhood ObesityR01ES021357 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA, WRIGHT, ROBERT O · 2012 to 2016
$3.3MEpigenetic Mechanisms of PM-Mediated CVD RiskR01ES020836 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BACCARELLI, ANDREA, HOU, LIFANG · 2012 to 2016
$3.0MMolecular and Epigenetic Mitochondriomics of Air Particles, Lead and CognitionR01ES021733 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA · 2012 to 2015
$2.4MAir Pollution, Epigenetics and Cardiovascular Health: A Human Intervention TrialR21ES021895 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA · 2012 to 2013
$376kNIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES020836NIEHS NIH HHS R01 ES021357NIEHS NIH HHS R01 ES021733NIEHS NIH HHS R21 ES021895NIEHS NIH HHS T32 ES007142
Abstract
Ambient fine particle (PM
Indexed as
AdultAutonomic Nervous SystemCross-Over StudiesElectrocardiographyFemaleFolic AcidHeart RateHumansInflammationLymphocyte CountMaleMiddle AgedParticle SizeParticulate MatterPilot ProjectsSingle-Blind MethodFolic AcidParticulate MatterVitamin B 12Vitamin B 6Vitamin B Complex
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT01864824ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.