ArticleNeurologia medico-chirurgica2017
The Effect of Irrigation Solutions on Recurrence of Chronic Subdural Hematoma: A Consecutive Cohort Study of 234 Patients.
Article in Neurologia medico-chirurgica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Irrigation practices in surgical evacuation of chronic subdural hematoma: systematic review and meta-analysis of technique, fluid type, and temperature.Neurosurgical review · 2025Pooled it
- Racial and ethnic differences in restarting antiplatelet therapy in patients with primary intracranial hemorrhage: a systematic review and meta-analysis.BMC neurology · 2024Pooled it
- The effects of antithrombotic drugs on the recurrence and mortality in patients with chronic subdural hematoma: A meta-analysis.Medicine · 2019Pooled it
- Optimal drain position after evacuation of chronic subdural hematomas: a systematic review and network meta-analysis.Frontiers in neurologyPooled it
- Robot-assisted stereotactic minimally invasive aspiration and irrigation (RASMIAI): a novel approach for severe intraventricular hemorrhage.Neurosurgical review · 2025Article
- Article
- The clinical differences between traumatic and NOS chronic subdural hematoma.Frontiers in neurology · 2024Article
- Artificial cerebrospinal fluid use during burr-hole surgery and reoperation rate in patients with chronic subdural hematoma: an analysis using a nationwide inpatient database.Acta neurochirurgica · 2023Article
- Chronic Subdural Hematoma-Evolution of Etiology and Surgical Treatment.Neurologia medico-chirurgica · 2023Review
- Surgical techniques for evacuation of chronic subdural hematoma: a mini-review.Frontiers in neurology · 2023Review
- Intraoperative irrigation of artificial cerebrospinal fluid and temperature of irrigation fluid for chronic subdural hematoma: a systematic review and meta-analysis.Frontiers in neurology · 2023Review
- Half-Saline Versus Normal-Saline as Irrigation Solutions in Burr Hole Craniostomy to Treat Chronic Subdural Hematomata: A Randomized Clinical Trial.Korean journal of neurotrauma · 2022Article
- Controversies in the Surgical Treatment of Chronic Subdural Hematoma: A Systematic Scoping Review.Diagnostics (Basel, Switzerland) · 2022Article
- Endoscopic surgery for intraventricular hemorrhage: A comparative study and single center surgical experience.World journal of clinical cases · 2022Article
- Clinical Characteristics and Current Managements for Patients with Chronic Subdural Hematoma : A Retrospective Multicenter Pilot Study in the Republic of Korea.Journal of Korean Neurosurgical Society · 2022Article
- Randomized controlled study on the curative effects of twist-drill craniotomy and burr-hole craniotomy in the treatment of chronic subdural hematoma.Experimental and therapeutic medicine · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic subdural hematomas (CSDHs) occur often in elderly persons and can occur with mild head trauma. With burr-hole irrigation as standard treatment, symptoms usually improve and can be cured, and outcomes are good, but postoperative recurrences are a common problem. This study investigated the effectiveness and recurrence rates when using artificial cerebrospinal fluid (ACF) instead of normal saline (NS) as an irrigation solution for burr-hole irrigation in patients with CSDH. This prospective study included 234 consecutive patients who underwent initial surgical treatment by burr-hole irrigation for a CSDH between April 2008 and June 2015. The irrigation solution used was changed from NS to ACF in June 2011. Factors examined with regard to recurrence included age, sex, unilateral or bilateral surgery, computed tomography (CT) findings, antiplatelet or anticoagulant drug use, past history, and irrigation solution (NS or ACF). These were analyzed by univariate and multivariate analyses. Univariate analyses (chi-square test) with a significance level <5% showed that recurrence rates were significantly lower in the ACF group than in the NS group (P = 0.003). Multivariate analysis (multiple logistic regression analysis) showed that the risk of recurrence was reduced 3.14-fold in the ACF group compared to the NS group (odds ratio, 3.143; 95% confidence interval, 0.1504-0.6733; P = 0.0028). None of the other factors were significantly different. In burr-hole irrigation for CSDH, the use of ACF instead of NS as an irrigation solution significantly reduces recurrence rates.
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