Evidence map›Paper›PMID 28367612›Full record

ReviewIndian journal of pediatrics2017

Management of Wilms Tumor: ICMR Consensus Document.

Maya Prasad, Tushar Vora, Sandeep Agarwala, Siddharth Laskar, Brijesh Arora, Deepak Bansal, Gauri Kapoor, Girish Chinnaswamy, Venkatraman Radhakrishnan, Tanvir Kaur and 2 more

Abstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Indian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Wilms Tumor in India: A Systematic Review.South Asian journal of cancer · 2023
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Wilms' Tumor - An Audit.Journal of Indian Association of Pediatric Surgeons
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Maya PrasadDepartment of Pediatric Oncology, Tata Memorial Hospital, Parel, Mumbai, 400012, India.
Tushar VoraDepartment of Pediatric Oncology, Tata Memorial Hospital, Parel, Mumbai, 400012, India. tusharsvora@yahoo.com.ORCID http://orcid.org/0000-0001-5469-056X
Sandeep AgarwalaDepartment of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.
Siddharth LaskarDepartment of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India.
Brijesh AroraDepartment of Pediatric Oncology, Tata Memorial Hospital, Parel, Mumbai, 400012, India.
Deepak BansalPediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gauri KapoorDepartment of Pediatric Hematology & Oncology, Rajiv Gandhi Cancer Institute & Research Center, Delhi, India.
Girish ChinnaswamyDepartment of Pediatric Oncology, Tata Memorial Hospital, Parel, Mumbai, 400012, India.
Venkatraman RadhakrishnanDepartment of Medical Oncology and Pediatric Oncology, Cancer Institute (W.I.A), Adyar, Chennai, India.
Tanvir KaurNCD Division, Indian Council of Medical Research (ICMR), New Delhi, India.
G K RathDr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Sameer BakhshiDepartment of Medical Oncology, Dr. B.R.A Institute-Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Tata Memorial Hospital · INDR. B.R.A. Institute Rotary Cancer Hospital · INAll India Institute of Medical Sciences · INCancer Institute (WIA) · INIndian Council of Medical Research · INPost Graduate Institute of Medical Education and Research · INRajiv Gandhi Cancer Institute and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wilms tumor (WT) is the most common renal tumor of childhood. Although multidisciplinary care including surgery, chemotherapy and radiotherapy have greatly improved the survival rates in WT, there is a scope for further improvement in India and other resource-poor settings. In resource-limited settings, the majority of patients present with large tumors, which may either be unresectable or risky to resect; making preoperative chemotherapy followed by delayed surgery the preferred approach. Histology and staging are used for risk stratification. The imaging procedure of choice is Contrast Enhanced CT scan (CECT) of thorax/ abdomen and pelvis, which is to be done at presentation, as well as for re-evaluation. Surgery is the cornerstone of treatment in WT and Radical Nephroureterectomy and Lymph node sampling is the procedure of choice, to be performed at week 5 in Non Metastatic WT and week 7 in Metastatic WT. WT is an extremely chemosensitive and radiosensitive tumor. Preoperative chemotherapy for Non Metastatic WT consists of 4 wk of Vincristine /Actinomycin and 6 wk of Vincristine /Actinomycin/ Adriamycin for Metastatic WT, with post-operative chemotherapy depending on stage and histology. Radiation therapy is recommended mainly in Stage III and Stage IV WT, with other indications given in the text. Other recommendations, such as treatment of WT in special situations and for supportive care are also detailed in the text.

Indexed as

ChildCombined Modality TherapyHumansIndiaKidney NeoplasmsWilms TumorICMR guidelinesWilms tumor

Identifiers

PMID28367612
OpenAlexW2602306976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.