Evidence map›Paper›PMID 28367491›Full record

ArticleTheScientificWorldJournal2017

Alpha-Amylase Inhibition and Antioxidative Capacity of Some Antidiabetic Plants Used by the Traditional Healers in Southeastern Nigeria.

Sunday O Oyedemi, Blessing O Oyedemi, Ifeoma I Ijeh, Princemartins E Ohanyerem, Roger M Coopoosamy, Olayinka A Aiyegoro

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 133 citations in OpenAlex.

  1. DomesticatedInternational journal of molecular sciences · 2026
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  4. Metabolite profiling and molecular dynamics-basedFrontiers in plant science · 2026
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  12. Synthesis and Characterization of Baicalein-loaded Aquasomes: AnCurrent drug discovery technologies · 2024
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  13. Scientifica · 2024
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  14. Article
  15. Article
  16. Review
  17. Article
  18. Microencapsulation ofScientifica · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sunday O OyedemiDepartment of Nature Conservation and Ethnobotany, Mangosuthu University of Technology P.O. Box 12363, Jacobs, Durban 4026, South Africa.ORCID 0000-0002-0897-2598
Blessing O OyedemiDepartment of Plant Science and Biotechnology, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Ifeoma I IjehDepartment of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Princemartins E OhanyeremDepartment of Plant Science and Biotechnology, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Roger M CoopoosamyDepartment of Nature Conservation and Ethnobotany, Mangosuthu University of Technology P.O. Box 12363, Jacobs, Durban 4026, South Africa.ORCID 0000-0003-4418-8626
Olayinka A AiyegoroGI Microbiology and Biotechnology Unit, Agricultural Research Council, Animal Production Institute, Irene, Pretoria 0062, South Africa.
Michael Okpara University of Agriculture · NGMangosuthu University of Technology · ZAAnimal Production Institute · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress plays a significant role in the pathogenesis of metabolic syndrome including diabetes mellitus (DM). The inhibition of alpha-amylase is an important therapeutic target in the regulation of postprandial increase of blood glucose in diabetic patients. The present study investigated the alpha-amylase inhibitory and antioxidant potential of selected herbal drugs used in the treatment of DM by the traditional healers in Isiala Mbano and Ikwuano regions of southeastern Nigeria. Antioxidant activity was evaluated in terms of free radical scavenging, reducing power, and total phenolic (TPC) and flavonoid content (TFC) in consonance with the TLC profiling. The results showed that methanol crude extracts from

Indexed as

alpha-AmylasesAntioxidantsHumansHypoglycemic AgentsNigeriaPhenolsPlant ExtractsPlants, Medicinalalpha-AmylasesAntioxidantsHypoglycemic AgentsPhenolsPlant Extracts

Identifiers

PMID28367491
PMCPMC5358441
OpenAlexW2594088552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.