Genetic Analysis of Southwestern Iranian Patients with Familial Mediterranean Fever.

Mahmoud Haghighat, Mozhgan Moghtaderi, Shirin Farjadian

Open access · greenAbstract read

In one paragraph

Article in Reports of biochemistry & molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.2field-weighted citation impact, top 45% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

Clinical and genetic characterization of familial Mediterranean fever among a cohort of Egyptian patients.Przeglad gastroenterologiczny · 2022
Article
Prevalence of MEFV gene mutations in a large cohort of patients with suspected familial Mediterranean fever in Central Anatolia.Annals of Saudi medicine
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mahmoud HaghighatGastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran.

Mozhgan MoghtaderiAllergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Shirin FarjadianAllergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Immunology, Shiraz University of Medical Sciences, Shiraz, Iran.

Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFamilial Mediterranean fever (FMF) is an autosomal recessive genetic disorder characterized by recurrent episodes of self-limited fever and serosal tissues inflammation.

methodsTo evaluate clinical symptoms and common genetic mutations in southwestern Iranian patients with FMF, 20 unrelated patients were enrolled in this study based on clinical criteria. A panel of 12 common

resultsThe most frequent clinical presentations of the patients were fever, colicky abdominal pain and arthritis. Eighteen patients responded completely to colchicine therapy.

conclusionsAlthough none of the 12 mutations we included in our test panel was detected in 60% of our patients, all of them had FMF symptoms and responded well to colchicine.

Indexed as

Familial Mediterranean fever>MEFV gene mutations

Identifiers

PMID28367474

PMCPMC5346280

OpenAlexW2586297925

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.