ArticleFrontiers in pediatrics2017
Heart Rate and Blood Pressure Centile Curves and Distributions by Age of Hospitalized Critically Ill Children.
Article in Frontiers in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Cardiovascular Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Impaired Cerebral Autoregulation in Pediatric Patients with ECMO: A Retrospective Analysis of ECMO Time Periods and Association with Neurologic Injury.Neurocritical care · 2026Observational
- Association of Dynamic Arterial Elastance With Fluid Responsiveness in Critically Ill Children.Critical care explorations · 2025Observational
- Defining systolic blood pressure normative values in hospitalized pediatric patients: a single center experience.Pediatric research · 2024Observational
- Exploring the clinical relevance of vital signs statistical calculations from a new-generation clinical information system.Scientific reports · 2023Observational
- iCVS-Inferring Cardio-Vascular hidden States from physiological signals available at the bedside.PLoS computational biology · 2023Article
- Hypertension, Blood Pressure Variability, and Acute Kidney Injury in Hospitalized Children.Journal of the American Heart Association · 2023Article
- Normative data in resting and maximum heart rates and a prediction equation for young Tunisian soccer players: a cross-sectional study.EXCLI journal · 2023Article
- Hemodynamic instability during connection to continuous kidney replacement therapy in critically ill pediatric patients.Pediatric nephrology (Berlin, Germany) · 2022Article
- The association between prehospital vital signs of children and their critical clinical outcomes at hospitals.Scientific reports · 2022Observational
- Blood Pressure in Critically Ill Children: Exploratory Analyses of Concurrent Invasive and Noninvasive Measurements.Critical care explorations · 2021Article
- Hemodynamic Patterns Before Inhospital Cardiac Arrest in Critically Ill Children: An Exploratory Study.Critical care explorations · 2021Article
- [Paediatric Life Support].Notfall & rettungsmedizin · 2021Review
- Clinical Classification of Cold and Warm Shock: Is There a Signal in the Noise?Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020Article
- Recommendations for hemodynamic monitoring for critically ill children-expert consensus statement issued by the cardiovascular dynamics section of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).Critical care (London, England) · 2020Article
- Association between hypotension and serious illness in the emergency department: an observational study.Archives of disease in childhood · 2020Observational
- Evaluation and management of elevated blood pressures in hospitalized children.Pediatric nephrology (Berlin, Germany) · 2019Review
- Data Science for Child Health.The Journal of pediatrics · 2019Review
- Predicting individual physiologically acceptable states at discharge from a pediatric intensive care unit.Journal of the American Medical Informatics Association : JAMIA · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart rate (HR) and blood pressure (BP) form the basis for monitoring the physiological state of patients. Although norms have been published for healthy and hospitalized children, little is known about their distributions in critically ill children. The objective of this study was to report the distributions of these basic physiological variables in hospitalized critically ill children. Continuous data from bedside monitors were collected and stored at 5-s intervals from 3,677 subjects aged 0-18 years admitted over a period of 30 months to the pediatric and cardiac intensive care units at a large quaternary children's hospital. Approximately 1.13 billion values served to estimate age-specific distributions for these two basic physiological variables: HR and intra-arterial BP. Centile curves were derived from the sample distributions and compared to common reference ranges. Properties such as kurtosis and skewness of these distributions are described. In comparison to previously published reference ranges, we show that children in these settings exhibit markedly higher HRs than their healthy counterparts or children hospitalized on in-patient wards. We also compared commonly used published estimates of hypotension in children (e.g., the PALS guidelines) to the values we derived from critically ill children. This is a first study reporting the distributions of basic physiological variables in children in the pediatric intensive care settings, and the percentiles derived may serve as useful references for bedside clinicians and clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.