Evidence map›Paper›PMID 28367429›Full record

SynthesisCanadian journal of gastroenterology & hepatology2017

The Efficacy and Safety of 12 Weeks of Sofosbuvir and Ledipasvir versus Sofosbuvir, Ledipasvir, and Ribavirin in Patients with Chronic Hepatitis C, Genotype 1, Who Have Cirrhosis and Have Failed Prior Therapy: A Systematic Review and Meta-Analysis.

William Stokes, Carol Fenton, Fiona Clement, Matthew James, Paul Ronksley, Karen L Tang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Canadian journal of gastroenterology & hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Real-World Data from Turkey: Is Sofosbuvir/Ledipasvir With or Without Ribavirin Treatment for Chronic Hepatitis C Really Effective?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

William StokesDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403 29th St. NW, Calgary, AB, Canada T2N 2T9.ORCID 0000-0002-8684-0494
Carol FentonDepartment of Community Health Sciences, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.
Fiona ClementDepartment of Community Health Sciences, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.ORCID 0000-0003-0209-9457
Matthew JamesDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403 29th St. NW, Calgary, AB, Canada T2N 2T9; Department of Community Health Sciences, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.
Paul RonksleyDepartment of Community Health Sciences, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.ORCID 0000-0002-3958-7561
Karen L TangDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403 29th St. NW, Calgary, AB, Canada T2N 2T9; Department of Community Health Sciences, University of Calgary, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, Canada T2N 4N1.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsBenzimidazolesFluorenesGenotypeHepatitis C, ChronicHumansLiver CirrhosisRibavirinSofosbuvirAntiviral AgentsBenzimidazolesFluorenesledipasvirRibavirinSofosbuvir

Identifiers

PMID28367429
PMCPMC5358456
OpenAlexW2593362567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.