ArticleJournal of diabetes and metabolic disorders2017
Amino acid profiling in the gestational diabetes mellitus.
Article in Journal of diabetes and metabolic disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Association of maternal blood metabolomics and gestational diabetes mellitus risk: a systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2025Pooled it
- Comparison of Diagnostic Values of Maternal Arginine Concentration for Different Pregnancy Complications: A Systematic Review and Meta-Analysis.Biomedicines · 2022Pooled it
- Prenatal Amino Acid Supplementation to Improve Fetal Growth: A Systematic Review and Meta-Analysis.Nutrients · 2020Pooled it
- Amino Acid Profile Alterations in the Mother-Fetus System in Gestational Diabetes Mellitus and Macrosomia.International journal of molecular sciences · 2025Article
- Subcutaneous adipose tissue compensates for the perturbations in circulating one-carbon metabolism in women with gestational diabetes.Acta diabetologica · 2025Article
- Some Levels of Plasma Free Fatty Acids and Amino Acids in the Second Trimester Are Linked to Gestational Diabetes and Are Predictive of Persisting Impaired Glucose Tolerance After Delivery.Journal of clinical medicine · 2025Article
- Serum Amino Acid Variations in Obesity and Gestational Diabetes During Pregnancy.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Neonatal amino acid metabolism in gestational diabetes mellitus mothers treated with different treatment strategies.Journal of diabetes and metabolic disorders · 2025Article
- Article
- Omics experiments in Iran, a review in endocrine and metabolism disorders studies.Journal of diabetes and metabolic disorders · 2024Review
- Microbiome-derived metabolites in early to mid-pregnancy and risk of gestational diabetes: a metabolome-wide association study.BMC medicine · 2024Article
- Association between serum branched chain amino acids, mammalian target of rapamycin levels and the risk of gestational diabetes mellitus: a 1:1 matched case control study.BMC pregnancy and childbirth · 2024Article
- Correlation between newborn weight and serum BCAAs in pregnant women with diabetes.Nutrition & diabetes · 2024Article
- Exposure to endocrine disrupting chemicals impacts immunological and metabolic status of women during pregnancy.Molecular and cellular endocrinology · 2023Article
- Predictive Gestational Diabetes Biomarkers With Sustained Alterations Throughout Pregnancy.Journal of the Endocrine Society · 2022Review
- Branched-chain and aromatic amino acid levels response to an oral glucose load associated with gestational diabetes mellitus.Scientific reports · 2022Article
- Dynamic changes and early predictive value of branched-chain amino acids in gestational diabetes mellitus during pregnancy.Frontiers in endocrinology · 2022Article
- Early markers of gestational diabetes mellitus: what we know and which way forward?Biochemia medica · 2021Review
- Establishment of clinical diagnostic models using glucose, lipid, and urinary polypeptides in gestational diabetes mellitus.Journal of clinical laboratory analysis · 2021Article
- Mass spectrometry with derivatization method for concurrent measurement of amino acids and acylcarnitines in plasma of diabetic type 2 patients with diabetic nephropathy.Journal of diabetes and metabolic disorders · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of gestational diabetes mellitus (GDM) is increasing globally which is associated with various side effects for mothers and fetus. It seems that metabolomic profiling of the amino acids may be useful in early diagnosis of metabolic diseases. This study aimed to explore the association of the amino acids profiles with GDM.
methodsEighty three pregnant women with gestational age ≥25 weeks were randomly selected among pregnant women referred to prenatal care clinic in Arash hospital of Tehran, Iran. Women divided into three groups including 1) 25 pregnant women with normal glucose tolerance test, 2) 27 pregnant women with diabetes type 2 (T2D) (n: 27) and 3) 31 women with GDM (n: 31). Plasma levels of amino acids were measured by high performance liquid chromatography and were compared in three groups. Statistical analysis was performed using SPSS 16.
resultsCompared with normal mothers, GDM mothers showed higher plasma concentrations of Arginine (
conclusionsAmino acids levels are associated with risk of GDM and diabetes mellitus. However further prospective studies are needed to clarify the role of different metabolites involved in mechanism of GDM.
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