Evidence map›Paper›PMID 28367421›Full record

ArticleCell journal

Coadministration of Dexamethasone and

Seyed Ruhollah Hosseini, Gholamreza Kaka, Mohammad Taghi Joghataei, Mehdi Hooshmandi, Seyed Homayoon Sadraie, Kayvan Yaghoobi, Korosh Mansoori, Alireza Mohammadi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Seyed Ruhollah HosseiniNeuroscience Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Gholamreza KakaNeuroscience Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mohammad Taghi JoghataeiDepartment of Anatomy, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mehdi HooshmandiNeuroscience Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Homayoon SadraieDepartment of Anatomy, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Kayvan YaghoobiNeuroscience Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Korosh MansooriDepartment of Physical Medicine and Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Alireza MohammadiNeuroscience Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Baqiyatallah University of Medical Sciences · IRIran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSpinal cord injury (SCI) causes inflammation, deformity and cell loss. It has been shown that MATERIALS AND

methodsThirty six adult male Wistar rats were used in this experimental study. The weight-drop contusion method was employed to induce spinal cord injury in rats. DEX and MO were administrated alone and together in different treatment groups. Intra-muscular injection of DEX (1 mg/kg) was started three hours after injury and continued once a day for seven days after injury. Intra-peritoneal (I.P) injection of MO (150 mg/ kg) was started one day after injury and continued once a day for 14 days.

resultsOur results showed motor and sensory functions were improved significantly in the group received a combination of DEX and MO, compared to spinal cord injury group. Mean cavity area was decreased and loss of lower motor neurons and astrogliosis in the ventral horn of spinal cord was significantly prevented in the group received combination of DEX and

conclusionResults showed that combination of DEX and MO could be considered as a neuroprotective agent in spinal cord injury.

Indexed as

DexamethasoneMelissa officinalisNeuroprotectiveSpinal Cord Injury

Identifiers

PMID28367421
PMCPMC5241506
OpenAlexW2594268404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.