Evidence map›Paper›PMID 28367412›Full record

ReviewCell journal

A Review on Various Uses of N-Acetyl Cysteine.

Vida Mokhtari, Parvaneh Afsharian, Maryam Shahhoseini, Seyed Mehdi Kalantar, Ashraf Moini

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Cell journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 167 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 2 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04460521 phase4recruitingnot on this map

The Use of N-acetylcysteine Supplementation in Addition to Night Splinting for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized, Double-blind, Placebo-controlled Trial

TypeinterventionalSponsorEmily KraussRan2022 to 2026Enrolled240ConditionsCarpal Tunnel Syndrome, Hand Injuries and Disorders, Nerve Compression, SplintsArmsN-Acetyl cysteine, Wrist Splint
NCT04557215 phase1 / phase2completednot on this map

Evaluation of the Efficacy and Safety of Rifaximin in Combination With N-acetylcysteine (NAC) in Adult Patients With Irritable Bowel Syndrome With Diarrhea

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2020 to 2022Enrolled45ConditionsIrritable Bowel Syndrome With DiarrheaArmsRifaximin, N-acetylcysteine, Placebo
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 2 syntheses or guidelines pooled it, 307 citations in OpenAlex.

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107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vida MokhtariDepartment of Molecular Cytogenetics, Research and Clinical Center for Infertility, University of Medical Sciences, Yazd, Iran; Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran; Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Parvaneh AfsharianDepartment of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Maryam ShahhoseiniDepartment of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Seyed Mehdi KalantarDepartment of Molecular Cytogenetics, Research and Clinical Center for Infertility, University of Medical Sciences, Yazd, Iran.
Ashraf MoiniDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran; Department of Obstetrics and Gynecology, Roointan-Arash Hospital, Tehran, Iran.
Royan Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-acetyl cysteine (NAC), as a nutritional supplement, is a greatly applied antioxidant

Indexed as

AntioxidantN-Acetyl CysteineOxidative Stress

Identifiers

PMID28367412
PMCPMC5241507
OpenAlexW2625080994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.