Evidence map›Paper›PMID 28367384›Full record

ArticleCureus2017

Pilocytic Astrocytoma Enlargement Following Irradiation: Relapse or Pseudoprogression?

Yury Trunin, Andrey V Golanov, Valery V Kostjuchenko, Mikhail Galkin, Alexander N Konovalov

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yury TruninRadiology and Radiosurgery, Burdenko Neurosurgery Institute.
Andrey V GolanovDepartment of Radiation Oncology, Burdenko Neurosurgery Institute.
Valery V KostjuchenkoGamma Knife, Neurosurgery Business Center.
Mikhail GalkinDepartment of Radiation Oncology, Burdenko Neurosurgical Institute.
Alexander N KonovalovBurdenko Neurosurgery Institute.
Burdenko Neurosurgery Institute · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pilocytic astrocytomas are the most common gliomas (World Health Organization (WHO) grade 1) in children. According to many authors, stereotactic irradiation (radiotherapy and radiosurgery) is an effective method that provides a prolonged, recurrence-free survival in patients who have had partial tumor removal or in patients with an unresectable tumor. We present a case of a patient with midbrain pilocytic astrocytoma that enlarged considerably in the first six months after irradiation and then diminished in size during the next six months without any antitumor treatment. The clinical and radiological follow-up data for this patient, the surgery results for similar patients, and the data from other authors led us to the conclusion that early tumor volume enlargement after irradiation is usually pseudoprogression.

Indexed as

irradiationpilocytic astrocytomapseudoprogressionradiotherapy

Identifiers

PMID28367384
PMCPMC5360383
OpenAlexW2590766333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.