Evidence map›Paper›PMID 28367334›Full record

Trial reportNeural plasticity2017

Changes in Cortical Activation Patterns in Language Areas following an Aerobic Exercise Intervention in Older Adults.

Joe Nocera, Bruce Crosson, Kevin Mammino, Keith M McGregor

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01787292 (Effects of Exercise Intervention on Aging-related Motor Decline), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01787292 nacompletednot on this map

Effects of Exercise Intervention on Aging-related Motor Decline (AGING)

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2013 to 2019Enrolled33ConditionsAging, ExerciseArmsStretching Exercise Intervention, Aerobic Exercise Intervention, Self Monitoring
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. The effect of exercise on the improvement of verbal fluency, spatial working memory, and the three major executive functions in elderly alzheimer's patients: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  6. Effectiveness of A Pilates Training Program on Cognitive and Functional Abilities in Postmenopausal Women.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joe NoceraVA Rehabilitation R&D Center for Visual and Neurocognitive Rehabilitation, Atlanta VAMC, Decatur, GA, USA; Department of Neurology, Emory University, Atlanta, GA, USA.ORCID 0000-0002-3338-9927
Bruce CrossonVA Rehabilitation R&D Center for Visual and Neurocognitive Rehabilitation, Atlanta VAMC, Decatur, GA, USA; Department of Neurology, Emory University, Atlanta, GA, USA.
Kevin MamminoVA Rehabilitation R&D Center for Visual and Neurocognitive Rehabilitation, Atlanta VAMC, Decatur, GA, USA.
Keith M McGregorVA Rehabilitation R&D Center for Visual and Neurocognitive Rehabilitation, Atlanta VAMC, Decatur, GA, USA; Department of Neurology, Emory University, Atlanta, GA, USA.

Funding

Aerobic Exercise and Cognitive Training in Older AdultsIK2RX000744 · VA · VETERANS HEALTH ADMINISTRATION · PI NOCERA, JOE ROBERT · 2012 to 2017
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Effects of exercise intervention on aging-related motor declineIK2RX000956 · VA · VETERANS HEALTH ADMINISTRATION · PI MCGREGOR, KEITH MATTHEW · 2015 to 2017
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RRD VA IK2 RX000744RRD VA IK2 RX000956
6 · The paper itself

Abstract

Previous work has shown that older adults who evidence increased right inferior frontal gyrus (IFG) activity during language tasks show decreased sematic verbal fluency performance. The current study sought to evaluate if an aerobic exercise intervention can alter patterns of brain activity during a semantic verbal fluency task assessed by functional magnetic resonance imaging (fMRI). Thirty-two community-dwelling, sedentary older adults were enrolled to a 12-week aerobic "Spin" exercise group or a 12-week nonaerobic exercise control condition (Balance). Thirty participants completed their assigned intervention (16 Spin; 14 Balance) with pre- and postintervention assessments of a semantic verbal fluency task during fMRI and estimated VO

Indexed as

AgingExerciseSemanticsAgedBrain MappingCerebral CortexExercise TherapyFemaleFunctional LateralityGeriatric AssessmentHumansMagnetic Resonance ImagingMaleNeuropsychological TestsPrefrontal CortexVerbal Learning

Identifiers

PMID28367334
PMCPMC5358467

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.