ArticleInternational journal of fertility & sterility
Age as A Predictor of Embryo Quality Regardless of The Quantitative Ovarian Response.
Article in International journal of fertility & sterility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Anti-müllerian hormone as a predictor for live birth among women undergoing IVF/ICSI in different age groups: an update of systematic review and meta-analysis.Archives of gynecology and obstetrics · 2023Pooled it
- Use of Cumulative Live Birth Rate per Total Number of Embryos to Calculate the Success of IVF in Consecutive IVF Cycles in Women Aged ≥35 Years.BioMed research international · 2019Trial
- Co-culture with adipose mesenchymal stem cells promotes Blastocyst formation and gene expression in embryos from aged mice.Regenerative therapy · 2025Article
- Nomogram to predict the probability of clinical pregnancy in women with poor ovarian response undergoing in vitro fertilization/ intracytoplasmic sperm injection cycles.Archives of gynecology and obstetrics · 2024Article
- Development and validation of a nomogram model for predicting clinical pregnancy in endometriosis patients undergoing fresh embryo transfer.BMC pregnancy and childbirth · 2023Article
- The Relationship between Number of Supernumerary Blastocysts Cryopreserved and Probability of a Live Birth Outcome after Single Fresh Blastocyst Transfer: Analysis of over 10 Thousand Cycles.Journal of clinical medicine · 2023Article
- Comparison of clinical effects between early follicular prolonged GnRH agonist protocol and GnRH antagonist protocol in 3310 cycles: a retrospective study.BMC pregnancy and childbirth · 2022Article
- Prediction model of gonadotropin starting dose and its clinical application in controlled ovarian stimulation.BMC pregnancy and childbirth · 2022Article
- Correlation between anti-Müllerian hormone, age, and number of oocytes: A retrospective study in a Brazilian in vitro fertilization center.JBRA assisted reproduction · 2022Observational
- Machine Learning-Based Modeling of Ovarian Response and the Quantitative Evaluation of Comprehensive Impact Features.Diagnostics (Basel, Switzerland) · 2022Article
- Article
- Prediction of pregnancy outcome in freshAging · 2021Article
- Comparison of pregnancy outcomes using a time-lapse monitoring system for embryo incubation versus a conventional incubator in in vitro fertilization: An age-stratification analysis.Clinical and experimental reproductive medicine · 2021Article
- A novel embryo quality scoring system to compare groups of embryos at different developmental stages.Journal of assisted reproduction and genetics · 2021Article
- Factors related to infertility in Brazil and their relationship with success rates after assisted reproduction treatment: an integrative review.JBRA assisted reproduction · 2021Review
- Which ovarian reserve marker relates to embryo quality on day 3 and blastocyst; age, AFC, AMH?JBRA assisted reproduction · 2021Article
- Predictive Factors for Live Birth in FreshFrontiers in endocrinology · 2021Article
- Amyloid-like substance in mice and human oocytes and embryos.Journal of assisted reproduction and genetics · 2019Article
- A comparison of the effects of three luteal phase support protocols with estrogen on in vitro fertilization-embryo transfer outcomes in patients on a GnRH antagonist protocol.JBRA assisted reproduction · 2019Observational
- Are age and anti-Müllerian hormone good predictors of ovarian reserve and response in women undergoing IVF?JBRA assisted reproduction · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne determining factor of a successful MATERIALS AND
methodsIn this prospective study, 120 infertile women, aged 21-44 years, undergoing routine exploration during an unstimulated cycle preceding assisted reproductive technology (ART) at our center were studied prospectively, from February 2011 to December 2014. Descriptive parameters and patient characteristics were reported as mean (SD) or median (range) depending on the distribution. Student's t test was performed for continuous variables, Wilcoxon and Pearson's Test were used for not distributed variables and Fisher's Test was performed for categorical variables. P<0.05 was considered statistically significant.
resultsOverall, at the time of investigation, patients had a mean age of 33.03 ± 4.15 years old. On cycle day three, serum anti-Mullerian hormone (AMH) level was 3.50 ± 1.54 ng/mL, serum follicle-stimulating hormone (FSH) level was 6.29 ± 1.53 mUI/ mL, at baseline, women had 16.57 ± 7.0 antral follicles. The mean of collected oocytes was 11.80 ± 5.25, embryo I+II was 2.46 ± 2.11. A greater number of embryos I+II was observed in young patients. By evaluating 120 patients, a significant relationship was observed between age and FSH (r=0.24, P=0.01), age with AMH (r=-0.22, P=0.02), age with collected oocytes (r=-0.23, P=0.03) and age with embryo I+II (r=-0.22, P=0.03). A significant relationship was also observed between antral follicle count (AFC) and AMH (r=0.29, P=0.01), AFC and the number of transferred embryo (r=-0.18, P=0.03), AFC and total dose of the drugs (r=-0.23, P=0.03). Significant relationship of FSH with total dose of drugs (r=0.19, P=0.02) was also observed. In addition, we determined significant relationships between AMH and the number of collected oocytes (r=0.38, P=0.01), AMH and the number of metaphase II oocytes (r= 0.35, P=0.01), AMH and the number of embryo (r=0.19, P=0.04) as well as AMH and total dose of the drugs (r=-0.25, P=0.01).
conclusionCommonly used clinical markers of ovarian reserve are reflection of the ovarian reserve, while the outcome measurements of ART and age are the best predictors of embryo quality.
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