Evidence map›Paper›PMID 28367268›Full record

ArticleOxidative medicine and cellular longevity2017

Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210.

Tianyi Li, Xianjing Song, Jichang Zhang, Lei Zhao, Yongfeng Shi, Zhibo Li, Jia Liu, Ning Liu, Youyou Yan, Yanlong Xiao and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

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  16. Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  17. Article
  18. Oxidative Stress-Responsive MicroRNAs in Heart Injury.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tianyi LiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xianjing SongDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Jichang ZhangDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Lei ZhaoDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yongfeng ShiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhibo LiDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0002-4237-8613
Jia LiuDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Ning LiuDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Youyou YanDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0002-5582-2373
Yanlong XiaoDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xin TianDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0002-9414-005X
Wei SunDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yinuo GuanDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Bin LiuDepartment of Cardiology, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0003-2017-2160
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress induces endothelial cell apoptosis and promotes atherosclerosis development. MicroRNA-210 (miR-210) is linked with apoptosis in different cell types. This study aimed to investigate the role of miR-210 in human umbilical vein endothelial cells (HUVECs) under oxidative stress and to determine the underlying mechanism. HUVECs were treated with different concentrations of hydrogen peroxide (H

Indexed as

Oxidative StressApoptosisApoptosis Regulatory ProteinsCalcium-Binding ProteinsCaspase 3Caspase 8HumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideMicroRNAsReactive Oxygen SpeciesApoptosis Regulatory ProteinsCalcium-Binding ProteinsCASP8AP2 protein, humanCaspase 3Caspase 8Hydrogen PeroxideMicroRNAsReactive Oxygen Species

Identifiers

PMID28367268
PMCPMC5359453
OpenAlexW2591981148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.