Evidence map›Paper›PMID 28367205›Full record

ArticlePakistan journal of medical sciences

Lipid abnormalities in patients with Rheumatoid Arthritis.

Uzma Erum, Tasnim Ahsan, Danish Khowaja

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06724952 (Clinical Study Evaluating Anti Rheumatic Activity and The Role of Silymarin in Attenuating Methotrexate Toxicity in Patients With Rheumatoid Arthritis), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06724952 phase4not yet recruitingnot on this map

Clinical Study Evaluating Anti Rheumatic Activity and The Role of Silymarin in Attenuating Methotrexate Toxicity in Patients With Rheumatoid Arthritis

TypeinterventionalSponsorTanta UniversityRan2024 to 2025Enrolled44ConditionsRheumatoid Arthritis (RA)ArmsMTX S.C or IM and Silymarin 140 mg tab, MTX S.C or IM
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. [Correlation between dyslipidemia and rheumatoid arthritis associated interstitial lung disease].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. The Effect of TNF-Cardiology research and practice · 2022
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. [Serum lipid profile in children with different subtypes of juvenile idiopathic arthritis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Uzma ErumDr. Uzma Erum, MBBS, FCPS Trainee. Medical Unit-II, Rafiqee Shaheed Road, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Tasnim AhsanProf. Tasnim Ahsan, MRCP, FRCP, FRCP, FRCP. Medical Unit-II, Rafiqee Shaheed Road, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Danish KhowajaDr. Danish Khowaja, MBBS, FCPS Trainee. Medical Unit-II, Rafiqee Shaheed Road, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Jinnah Postgraduate Medical Center · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the frequency of dyslipidemia in patients with Rheumatoid Arthritis.

methodsThis is a prospective, cross-sectional, observational study, conducted at the 'Rheumatology Clinic' of Jinnah Postgraduate Medical Center (JPMC), Karachi, from November 2013 to May 2014. A total of 200 patients of Rheumatoid Arthritis (RA), diagnosed according to the ACR/EULAR criteria 2010, were included in the study. Laboratory investigations including creatinine, ALT, CBC, TSH and fasting lipid profile (LDL, HDL, and Total cholesterol) were done for all patients.

resultsOut of 200 patients, 23 (11.5%) were male and 177 (88.5%) were female. The mean age was 36.31±10.46 years and the mean duration of disease was 3.82±3.03 years. A total of 107 (53.5%) patients had dyslipidemia, and the commonest abnormality was a low HDL, seen in 83 (41.5 %) patients.

conclusionDyslipidemia was frequently observed in Rheumatoid Arthritis. This may be considered as a secondary impact of chronic inflammatory state, seen in RA. Lipid abnormalities should be sought at regular intervals, and corrective actions taken to mitigate increased cardiovascular disease risk.

Indexed as

CholesterolDyslipidemiaRheumatoid Arthritis

Identifiers

PMID28367205
PMCPMC5368315
OpenAlexW2588342184

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.