Evidence map›Paper›PMID 28367148›Full record

ArticleFrontiers in immunology2017

Reduction of T-Helper Cell Responses to Recall Antigen Mediated by Codelivery with Peptidoglycan

Rachel E Hewitt, Jack Robertson, Carolin T Haas, Laetitia C Pele, Jonathan J Powell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rachel E HewittDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK; Medical Research Council, Department of Mineral Science and Technology, Elsie Widdowson Laboratory, Cambridge, UK.
Jack RobertsonMedical Research Council, Department of Mineral Science and Technology, Elsie Widdowson Laboratory , Cambridge , UK.
Carolin T HaasMedical Research Council, Department of Mineral Science and Technology, Elsie Widdowson Laboratory , Cambridge , UK.
Laetitia C PeleMedical Research Council, Department of Mineral Science and Technology, Elsie Widdowson Laboratory , Cambridge , UK.
Jonathan J PowellDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK; Medical Research Council, Department of Mineral Science and Technology, Elsie Widdowson Laboratory, Cambridge, UK.
Medical Research Council · GBMRC Human Nutrition Research · GBUniversity of Cambridge · GB

Funding

Medical Research Council MC_U105960399Medical Research Council MR/R005699/1Medical Research Council U105960399
6 · The paper itself

Abstract

Naturally occurring intestinal nanomineral particles constituently form in the mammalian gut and trap luminal protein and microbial components. These cargo loaded nanominerals are actively scavenged by M cells of intestinal immune follicles, such as Peyer's patches and are passed to antigen-presenting cells. Using peripheral blood mononuclear cell populations as an

Indexed as

antigen-presenting cellsIL-10intestinal tolerancenanomineralpeptidoglycanprogrammed death receptor ligand 1T cells

Identifiers

PMID28367148
PMCPMC5355426
OpenAlexW2595240620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.